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Wbp4 Gene Detail
Summary
  • Symbol
    Wbp4
  • Name
    WW domain binding protein 4
  • Synonyms
    FBP21
  • Feature Type
    protein coding gene
  • IDs
    MGI:109568
    NCBI Gene: 22380
  • Gene Overview
    MyGene.info: WBP4
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:79459937-79481268 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 42.66 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    37 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109568
protein coding gene Chr14:79459937-79481520 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021599
protein coding gene Chr14:74589272-74611156 (-)
A/J MGP_AJ_G0021557
protein coding gene Chr14:72730695-72753811 (-)
AKR/J MGP_AKRJ_G0021533
protein coding gene Chr14:74897071-74924012 (-)
BALB/cJ MGP_BALBcJ_G0021563
protein coding gene Chr14:72576766-72597655 (-)
C3H/HeJ MGP_C3HHeJ_G0021341
protein coding gene Chr14:74628952-74651286 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022003
protein coding gene Chr14:77752554-77776572 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019542
protein coding gene Chr14:70273116-70294872 (-)
CAST/EiJ MGP_CASTEiJ_G0020856
protein coding gene Chr14:71412559-71435822 (-)
CBA/J MGP_CBAJ_G0021309
protein coding gene Chr14:80250341-80275726 (-)
DBA/2J MGP_DBA2J_G0021433
protein coding gene Chr14:72134667-72156060 (-)
FVB/NJ MGP_FVBNJ_G0021409
protein coding gene Chr14:71477017-71497915 (-)
LP/J MGP_LPJ_G0021501
protein coding gene Chr14:75683578-75706465 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021437
protein coding gene Chr14:78912397-78933633 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022026
protein coding gene Chr14:74213631-74235559 (-)
PWK/PhJ MGP_PWKPhJ_G0020601
protein coding gene Chr14:68927979-68949957 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020437
protein coding gene Chr14:70188311-70209283 (-)
WSB/EiJ MGP_WSBEiJ_G0020911
protein coding gene Chr14:74569300-74592832 (-)



Homology
more
  • Human Ortholog
    WBP4, WW domain binding protein 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    WBP4, WW domain binding protein 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FBP21
  • Links
    NCBI Gene ID: 11193
    neXtProt AC: NX_O75554
    UniProt: O75554

  • Chr Location
    13q14.11; chr13:41061561-41084006 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 38287
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: WBP4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22380 NCBI Gene Model | MGI Sequence Detail 21332 C57BL/6J ±  kb
transcript NM_018765 RefSeq | MGI Sequence Detail 3452 C57BL/6  
polypeptide Q61048 UniProt | EBI | MGI Sequence Detail 376 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 16
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-39567, MGI:2145825, MGI:2145850
References
more
  • Summaries
    All 31
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:38792 Chan DC, et al., Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains. EMBO J. 1996 Mar 1;15(5):1045-54
  • Latest
    J:140465 Guo G, et al., Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory