Wbp4
Gene Detail

Symbol Name ID

Wbp4 WW domain binding protein 4 MGI:109568

Synonyms

FBP21

Feature Type

protein coding gene

Genetic Map

Chromosome 14

42.66 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr14:79459937-79481268 bp, - strand From NCBI annotation of GRCm38   21332 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:38287  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Wbp4

Human homologs

Human Homolog		WBP4, WW domain binding protein 4
NCBI Gene ID		11193
neXtProt AC		NX_O75554
Human Synonyms		FBP21
Human Chr (Location)		13q14.11; chr13:41635697-41658139 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(4) : Targeted(2) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	mRNA cis splicing, via spliceosome, mRNA processing, ...
Component	nuclear speck, nucleus, ...
Function	metal ion binding, nucleic acid binding, ...

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (43)    Tissues (29)    Images (3)
Theiler Stages: 2, 3, 4, 5, 23, 26, 28

Assay Type	Results
RNA in situ	24
Western blot	4
RT-PCR	15

cDNA source data(15)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(16) cDNA(15) Primer pair(1)
Microarray probesets(5)

Other database links

Ensembl Gene Model	ENSMUSG00000022023 (Evidence)
Entrez Gene	22380 (Evidence)
DFCI	TC1576048, TC1617891
NIA Mouse Gene Index	U035810
Consensus CDS Project	CCDS27300.1
International Mouse Knockout Project Status	Wbp4

Sequences

Length	Strain/Species
genomic	22380	NCBI Gene Model | MGI Sequence Detail	21332	C57BL/6J
transcript	NM_018765	RefSeq | MGI Sequence Detail	3452	C57BL/6
polypeptide	Q61048	UniProt | EBI | MGI Sequence Detail	376	Not Applicable

All sequences(28) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(37 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001202	WW/Rsp5/WWP
InterPro	IPR000690	Zinc finger, C2H2-type matrin
InterPro	IPR013085	Zinc finger, U1-C type
InterPro	IPR003604	Zinc finger, U1-type
Protein Ontology	PR:000017378	WW domain-binding protein 4

Graphical View of Protein Domain Structure

References

(Earliest) J:38792 Chan DC, et al., Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains. EMBO J. 1996 Mar 1;15(5):1045-54
(Latest) J:140465 Guo G, et al., Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85
All references(32)

Other accession IDs

MGD-MRK-39567, MGI:2145825, MGI:2145850