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Sp100 Gene Detail
Summary
  • Symbol
    Sp100
  • Name
    nuclear antigen Sp100
  • Synonyms
    A430075G10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:109561
    NCBI Gene: 20684
Location & Maps
more
  • Sequence Map
    Chr1:85649988-85709998 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      60011 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 43.60 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    SP100, SP100 nuclear antigen
  • Vertebrate Orthologs
    2
  • Human Ortholog
    SP100, SP100 nuclear antigen
    Orthology source: HGNC
  • Synonyms
    lysp100b
  • Links
    NCBI Gene ID: 6672
    neXtProt AC: NX_P23497

  • Chr Location
    2q37.1; chr2:230416156-230545602 (+)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Sp100
  • Incidental Mutations
    Mutagenetix , APF , CvDC
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    123
  • Tissues
    114
  • cDNA Data
    33
  • Literature Summary
    3
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030061 VEGA Gene Model | MGI Sequence Detail 60011 C57BL/6J ±  kb
transcript OTTMUST00000074556 VEGA | MGI Sequence Detail 2708 Not Applicable  
polypeptide OTTMUSP00000038883 VEGA | MGI Sequence Detail 591 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    238 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 48
    Genomic 11
    cDNA 37

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-39560, MGI:2443000
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:42499 Weichenhan D, et al., Structure and expression of the murine Sp100 nuclear dot gene. Genomics. 1997 Aug 1;43(3):298-306
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/20/2016
MGI 6.05 		The Jackson Laboratory