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Sp100 Gene Detail
Summary
  • Symbol
    Sp100
  • Name
    nuclear antigen Sp100
  • Synonyms
    A430075G10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:109561
    NCBI Gene: 20684
  • Alliance
    gene page
  • Transcription Start Sites
    22 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:85577709-85637719 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 43.60 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1384 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109561
 protein coding gene Chr1:85577683-85637719 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016233
 protein coding gene Chr1:86824029-86914415 (+)
A/J MGP_AJ_G0016214
 protein coding gene Chr1:83629535-83702115 (+)
AKR/J MGP_AKRJ_G0016175
 protein coding gene Chr1:86062545-86123699 (+)
BALB/cJ MGP_BALBcJ_G0016171
 protein coding gene Chr1:83764142-83827327 (+)
C3H/HeJ MGP_C3HHeJ_G0015999
 protein coding gene Chr1:86339060-86386457 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016625
 protein coding gene Chr1:90088011-90223832 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014348
 protein coding gene Chr1:78112571-78172676 (+)
CAST/EiJ MGP_CASTEiJ_G0015584
 protein coding gene Chr1:85572302-85618466 (+)
CBA/J MGP_CBAJ_G0015975
 protein coding gene Chr1:92972938-93043930 (+)
DBA/2J MGP_DBA2J_G0016077
 protein coding gene Chr1:82955680-83019911 (+)
FVB/NJ MGP_FVBNJ_G0016077
 protein coding gene Chr1:81875932-82067511 (+)
LP/J MGP_LPJ_G0016149
 protein coding gene Chr1:87955754-88023199 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016103
 protein coding gene Chr1:96257899-96335910 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016669
 protein coding gene Chr1:86171410-86246748 (+)
PWK/PhJ MGP_PWKPhJ_G0015371
 protein coding gene Chr1:82223813-82287870 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015151
 protein coding gene Chr1:85149052-85203820 (+)
WSB/EiJ MGP_WSBEiJ_G0015647
 protein coding gene Chr1:85852849-85904918 (+)



Homology
more
  • Human Ortholog
    SP100, SP100 nuclear antigen
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SP100, SP100 nuclear antigen
  • Synonyms
    lysp100b
  • Links
    NCBI Gene ID: 6672
    UniProt: P23497

  • Chr Location
    2q37.1; chr2:230415942-230545606 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    52
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    829
  • Tissues
    114
  • cDNA Data
    35
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026222 Ensembl Gene Model | MGI Sequence Detail 60011 C57BL/6J ±  kb
transcript ENSMUST00000066427 Ensembl | MGI Sequence Detail 2708 Not Applicable  
polypeptide ENSMUSP00000066399 Ensembl | MGI Sequence Detail 591 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 50
    Genomic 11
    cDNA 39

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-39560, MGI:2443000
References
more
  • Summaries
    All 43
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory