About   Help   FAQ
Terc
Gene Detail
 Symbol
Name
ID
Terc
telomerase RNA component
MGI:109558
BioType Conflict
Synonyms mTER, mTR
Feature Type telomerase RNA gene
Genetic Map
Chromosome 3
41.82 cM, cytoband F/G
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:96414437-96414833 bp, - strand
From NCBI annotation of GRCm38

  397 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Terc
Alleles
and
phenotypes
All alleles(2) : Targeted(1) Gene trapped(1)
 
Early generation mice homozygous for a null allele have intact telomeres and appear grossly unaffected and healthy, whereas late generation mutants exhibit premature death, shortened and dysfunctional telomeres, apoptotic and proliferative defects, infertility, and multi-organ degenerative decline.
 
Alleles Annotated to Human Diseases(1)    Phenotype Images(2)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process cell proliferation, hematopoietic stem cell differentiation, ...
Component telomerase holoenzyme complex
Function telomerase activity, template for synthesis of G-rich strand of telomere DNA activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (6)    Tissues (2)   
Theiler Stages: 20, 22
Assay TypeResults
Northern blot 6
cDNA source data(2)
External Resources: GEO  
Molecular
reagents
All nucleic(4) Genomic(2) cDNA(2)
Microarray probesets(1)
Other database
links
Ensembl Gene ModelENSMUSG00000064796 (Evidence)
Entrez Gene21748 (Evidence)
DFCITC1623162
DoTSDT.91282048
NIA Mouse Gene IndexU024386
International Mouse Knockout Project StatusTerc
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 21748 NCBI Gene Model | MGI Sequence Detail 397 C57BL/6J ±  kb
transcript NR_001579 RefSeq | MGI Sequence Detail 397 Not Specified 

For the selected sequences
All sequences(9) RefSeq(1)
Polymorphisms SNPs within 2kb(2 from dbSNP Build 137)
References (Earliest) J:28425 Blasco MA, et al., Functional characterization and developmental regulation of mouse telomerase RNA. Science. 1995 Sep 1;269(5228):1267-70
(Latest) J:205597 Le R, et al., Enhanced telomere rejuvenation in pluripotent cells reprogrammed via nuclear transfer relative to induced pluripotent stem cells. Cell Stem Cell. 2014 Jan 2;14(1):27-39
All references(155)
Other
accession IDs
MGD-MRK-39557

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/08/2014
MGI 5.17
The Jackson Laboratory