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Terc
Gene Detail
Symbol

Name
ID
Terc
telomerase RNA component
MGI:109558
BioType Conflict
Synonyms
mTER, mTR
Feature Type
telomerase RNA gene
Genetic Map
Chromosome 3
41.82 cM, cytoband F/G
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:96414437-96414833 bp, - strand
From NCBI annotation of GRCm38

  397 bp   ±  kb flank

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Mouse Genome Browser
Vertebrate
homology
Gene Tree: Terc
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
 
Early generation mice homozygous for a null allele have intact telomeres and appear grossly unaffected and healthy, whereas late generation mutants exhibit premature death, shortened and dysfunctional telomeres, apoptotic and proliferative defects, infertility, and multi-organ degenerative decline.
 
Alleles Annotated to Human Diseases(1)    Phenotype Images(2)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (6)    Tissues (2)    Tissue x Stage Matrix (view)
Assay TypeResults
Northern blot 6
cDNA source data(2)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(4) Genomic(2) cDNA(2)
Microarray probesets(1)
Other database
links
Ensembl Gene ModelENSMUSG00000064796 (Evidence)
Entrez Gene21748 (Evidence)
DFCITC1623162
DoTSDT.91282048
NIA Mouse Gene IndexU024386
International Mouse Knockout Project StatusTerc
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 21748 NCBI Gene Model | MGI Sequence Detail 397 C57BL/6J ±  kb
transcript NR_001579 RefSeq | MGI Sequence Detail 397 Not Specified 

For the selected sequences
All sequences(9) RefSeq(1)
Polymorphisms
SNPs within 2kb(2 from dbSNP Build 137)
References
(Earliest) J:28425 Blasco MA, et al., Functional characterization and developmental regulation of mouse telomerase RNA. Science. 1995 Sep 1;269(5228):1267-70
(Latest) J:213181 Brennan TA, et al., Mouse models of telomere dysfunction phenocopy skeletal changes found in human age-related osteoporosis. Dis Model Mech. 2014 May;7(5):583-92
All references(159)
Disease annotation references (1)
Other
accession IDs
MGD-MRK-39557

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory