About   Help   FAQ
Il4i1 Gene Detail
Summary
  • Symbol
    Il4i1
  • Name
    interleukin 4 induced 1
  • Synonyms
    Fig1, Fig1-ps
  • Feature Type
    protein coding gene
  • IDs
    MGI:109552
    NCBI Gene: 14204
Location & Maps
more
  • Sequence Map
    Chr7:44816387-44840809 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      24423 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 28.93 cM
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    IL4I1, interleukin 4 induced 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    IL4I1, interleukin 4 induced 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    FIG1, LAAO, LAO
  • Links
    NCBI Gene ID: 259307
    neXtProt AC: NX_Q96RQ9

  • Chr Location
    19q13.33; chr19:49889654-49929539 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutation of this gene results in no obvious phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029474 VEGA Gene Model | MGI Sequence Detail 24423 C57BL/6J ±  kb
transcript OTTMUST00000144840 VEGA | MGI Sequence Detail 2275 Not Applicable  
polypeptide OTTMUSP00000075453 VEGA | MGI Sequence Detail 638 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    171 from dbSNP Build 142
  • PCR
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 31
    Genomic 1
    cDNA 29
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-39551, MGI:892974
References
more
  • Summaries
    All 29
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:37359 Chu CC, et al., Fig1, an interleukin 4-induced mouse B cell gene isolated by cDNA representational difference analysis. Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2507-12
  • Latest
    J:229708 Cousin C, et al., The immunosuppressive enzyme IL4I1 promotes FoxP3(+) regulatory T lymphocyte differentiation. Eur J Immunol. 2015 Jun;45(6):1772-82

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory