Tnnt3
Gene Detail

Symbol Name ID

Tnnt3 troponin T3, skeletal, fast MGI:109550

Synonyms

fTnT, skeletal muscle fast-twitch TnT

Feature Type

protein coding gene

Genetic Map

Chromosome 7

87.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)

Sequence Map

Chr7:142498836-142516009 bp, + strand From VEGA annotation of GRCm38   17174 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:31405  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Gene Tree: Tnnt3

Human homologs

Human Homolog		TNNT3, troponin T type 3 (skeletal, fast)
NCBI Gene ID		7140
neXtProt AC		NX_P45378
Human Synonyms		TNTF
Human Chr (Location)		11p15.5; chr11:1940799-1959936 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human TNNT3

Alleles and phenotypes

All alleles(3) : Targeted(3)

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	regulation of ATPase activity, regulation of muscle contraction, ...
Component	troponin complex
Function	actin binding, calcium-dependent ATPase activity, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (17 records)
Data Summary: Results (155)    Tissues (44)    Images (31)
Theiler Stages: 15, 17, 20, 22, 23, 24, 25, 26, 28

Assay Type	Results
RNA in situ	97
RT-PCR	58

cDNA source data(95)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(105) Genomic(7) cDNA(95) Primer pair(3)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000018789 (Evidence)
Ensembl Gene Model	ENSMUSG00000061723 (Evidence)
Entrez Gene	21957 (Evidence)
UniGene	389992
DFCI	TC1579167, TC1587307, TC1587754, TC1588163, TC1588411, TC1588984, TC1592944, TC1627951, TC1639960
DoTS	DT.101387010, DT.102542534, DT.55100263, DT.94400177, DT.94400194, DT.97400372, DT.97400373
NIA Mouse Gene Index	U042875
Consensus CDS Project	CCDS22031.1, CCDS52451.1, CCDS52452.1, CCDS52453.1, CCDS52454.1, CCDS52455.1, CCDS52456.1, CCDS52457.1
International Mouse Knockout Project Status	Tnnt3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000018789	VEGA Gene Model | MGI Sequence Detail	17174	C57BL/6J
transcript	OTTMUST00000045214	VEGA | MGI Sequence Detail	1050	Not Applicable
polypeptide	OTTMUSP00000020328	VEGA | MGI Sequence Detail	272	Not Applicable

All sequences(166) RefSeq(16) UniProt(12)

Polymorphisms

RFLP(1) : SNPs(42 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001978	Troponin
Protein Ontology	PR:000016510	troponin T, fast skeletal muscle

References

(Earliest) J:39609 Koch A, et al., cDNA cloning and chromosomal mapping of mouse fast skeletal muscle troponin T. Mamm Genome. 1997 May;8(5):346-8
(Latest) J:193107 Jin C, et al., Deciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis. Dev Biol. 2013 Feb 1;374(1):96-107
All references(45)

Other accession IDs

MGD-MRK-39549