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Crybg1 Gene Detail
Summary
  • Symbol
    Crybg1
  • Name
    crystallin beta-gamma domain containing 1
  • Synonyms
    Aim1
  • Feature Type
    protein coding gene
  • IDs
    MGI:109544
    NCBI Gene: 11630
  • Alliance
    genome feature page
  • Transcription Start Sites
    29 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:43826632-44024849 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 23.14 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6003 from dbSNP Build 142
  • Strain Annotations
    19
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109544
 protein coding gene Chr10:43826303-44024849 (-)
129S1/SvImJ ENSMUSG00200006535
 protein coding gene Chr10:40721150-40919390 (-)
A/J ENSMUSG00195002828
 protein coding gene Chr10:40994212-41192434 (-)
AKR/J ENSMUSG00220005553
 protein coding gene Chr10:40680047-40878270 (-)
BALB/cJ ENSMUSG00180011390
 protein coding gene Chr10:41083495-41281699 (-)
C3H/HeJ ENSMUSG00175009987
 protein coding gene Chr10:40870915-41069128 (-)
C57BL/6NJ ENSMUSG00215002202
 protein coding gene Chr10:40620956-40819172 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015293
 protein coding gene Chr10:39486307-39683315 (-)
CAST/EiJ ENSTCUG00005008244
 protein coding gene Chr10:41070042-41267315 (-)
CBA/J ENSMUSG00210008164
 protein coding gene Chr10:40766595-40964804 (-)
DBA/2J ENSMUSG00185003191
 protein coding gene Chr10:40918112-41116314 (-)
FVB/NJ ENSMUSG00205004299
 protein coding gene Chr10:40833511-41031741 (-)
JF1/MsJ ENSUMUG00000024281
 protein coding gene Chr10:40717708-40914003 (-)
LP/J ENSMUSG00230005366
 protein coding gene Chr10:42719180-42917410 (-)
NOD/ShiLtJ ENSMUSG00190005395
 protein coding gene Chr10:41046348-41244542 (-)
NZO/HlLtJ ENSMUSG00225016983
 protein coding gene Chr10:47008056-47206207 (-)
PWK/PhJ ENSLUMGG00010054123
 protein coding gene Chr10:40825149-40878903 (-)
SPRET/EiJ ENSMSPG00010012775
 protein coding gene Chr10:41872031-42082628 (-)
WSB/EiJ ENSIUOG00005014666
 protein coding gene Chr10:40599513-40797459 (-)



Homology
more
  • Human Ortholog
    CRYBG1, crystallin beta-gamma domain containing 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CRYBG1, crystallin beta-gamma domain containing 1
  • Synonyms
    AIM1, ST4
  • Links
    NCBI Gene ID: 202
    UniProt: Q9Y4K1

  • Chr Location
    6q21; chr6:106360717-106572017 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    646
  • Tissues
    44
  • cDNA Data
    86
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000019866 Ensembl Gene Model | MGI Sequence Detail 198218 C57BL/6J ±  kb
    transcript ENSMUST00000200401 Ensembl | MGI Sequence Detail 7525 Not Applicable  
    polypeptide ENSMUSP00000143429 Ensembl | MGI Sequence Detail 2065 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 90
      Genomic 1
      cDNA 86
      Primer pair 2
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-39543, MGI:2143619, MGI:2143621, MGI:5883599
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 17
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory