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Cdh17
Gene Detail
Symbol

Name
ID
Cdh17
cadherin 17
MGI:1095414
Synonyms
BILL-cadherin, HPT-1, LI-cadherin
Feature Type
protein coding gene
Genetic Map
Chromosome 4
5.35 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:11758147-11817895 bp, + strand
From VEGA annotation of GRCm38

  59749 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56859  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Cdh17

Human
homologs
Human Homolog CDH17, cadherin 17, LI cadherin (liver-intestine)
NCBI Gene ID 1015
neXtProt AC  NX_Q12864
Human Synonyms  CDH16, HPT1, HPT-1
Human Chr (Location)  8q22.1; chr8:94127166-94217303 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(2) Spontaneous(1) Targeted(3)
Genomic Mutations involving Cdh17 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice exhibit impaired B lymphocyte development and impaired IgG1 and IgG3 antibody response to T-independent antigen.
 
Alleles Annotated to Human Diseases(1)   
Interactions
Cdh17 interacts with 181 markers (Mir22, Mir23a, Mir23b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (82)    Tissues (60)    Images (27)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 15
RNA in situ 44
Northern blot 15
Western blot 2
RT-PCR 6
cDNA source data(16)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(16) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000004521 (Evidence)
Ensembl Gene ModelENSMUSG00000028217 (Evidence)
Entrez Gene12557 (Evidence)
UniGene33402
DFCITC1607544, TC1580824
DoTSDT.101715332, DT.102532356, DT.487852
NIA Mouse Gene IndexU004072
Consensus CDS ProjectCCDS17972.1
International Mouse Knockout Project StatusCdh17
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004521 VEGA Gene Model | MGI Sequence Detail 59749 C57BL/6J ±  kb
transcript OTTMUST00000010244 VEGA | MGI Sequence Detail 3462 Not Applicable 
polypeptide OTTMUSP00000004872 VEGA | MGI Sequence Detail 827 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(6) UniProt(7)
Polymorphisms
SNPs within 2kb(230 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002126 Cadherin
InterPro IPR020894 Cadherin conserved site
InterPro IPR015919 Cadherin-like
Protein Ontology PR:000005235 cadherin-17
References
(Earliest) J:33453 Dantzig AH, et al., Association of intestinal peptide transport with a protein related to the cadherin superfamily. Science. 1994 Apr 15;264(5157):430-3
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory