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Cdh17
Gene Detail
 Symbol
Name
ID
Cdh17
cadherin 17
MGI:1095414
Synonyms BILL-cadherin, HPT-1, LI-cadherin
Feature Type protein coding gene
Genetic Map
Chromosome 4
5.35 cM, cytoband A2
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:11758147-11817895 bp, + strand
From VEGA annotation of GRCm38

  59749 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56859  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Cdh17

Human
homologs
Human Homolog CDH17, cadherin 17, LI cadherin (liver-intestine)
NCBI Gene ID 1015
neXtProt AC  NX_Q12864
Human Synonyms  CDH16, HPT1, HPT-1
Human Chr (Location)  8q22.1; chr8:94127166-94217303 (-)  GRCh38
Alleles
and
phenotypes
All alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice exhibit impaired B lymphocyte development and impaired IgG1 and IgG3 antibody response to T-independent antigen.
 
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process calcium-dependent cell-cell adhesion, cell adhesion, ...
Component basolateral plasma membrane, integral component of membrane, ...
Function calcium ion binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (82)    Tissues (60)    Images (27)
Theiler Stages: 10, 17, 18, 19, 20, 21, 22, 23, 24, 25, 27, 28
Assay TypeResults
Immunohistochemistry 15
RNA in situ 44
Northern blot 15
Western blot 2
RT-PCR 6
cDNA source data(16)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(17) cDNA(16) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000004521 (Evidence)
Ensembl Gene ModelENSMUSG00000028217 (Evidence)
Entrez Gene12557 (Evidence)
UniGene33402
DFCITC1580824, TC1607544
DoTSDT.487852, DT.101715332, DT.102532356
NIA Mouse Gene IndexU004072
Consensus CDS ProjectCCDS17972.1
International Mouse Knockout Project StatusCdh17
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004521 VEGA Gene Model | MGI Sequence Detail 59749 C57BL/6J ±  kb
transcript OTTMUST00000010244 VEGA | MGI Sequence Detail 3462 Not Applicable 
polypeptide OTTMUSP00000004872 VEGA | MGI Sequence Detail 827 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(6) UniProt(4)
Polymorphisms SNPs within 2kb(230 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002126 Cadherin
InterPro IPR020894 Cadherin conserved site
InterPro IPR015919 Cadherin-like
Protein Ontology PR:000005235 cadherin-17
References (Earliest) J:33453 Dantzig AH, et al., Association of intestinal peptide transport with a protein related to the cadherin superfamily. Science. 1994 Apr 15;264(5157):430-3
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory