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Tuba3a Gene Detail
Summary
  • Symbol
    Tuba3a
  • Name
    tubulin, alpha 3A
  • Synonyms
    M[a]3, Tuba3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1095406
    NCBI Gene: 22144
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:125278274-125286042 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 59.32 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    110 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1095406
protein coding gene Chr6:125278274-125286042 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0031264
protein coding gene Chr6:123766439-123774571 (-)
AKR/J MGP_AKRJ_G0031192
protein coding gene Chr6:127142669-127150401 (-)
BALB/cJ MGP_BALBcJ_G0031464
protein coding gene Chr6:144423150-144424688 (+)
C3H/HeJ MGP_C3HHeJ_G0030995
protein coding gene Chr6:127214256-127223747 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031728
protein coding gene Chr6:132010028-132017826 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028877
protein coding gene Chr6:120976680-120985664 (-)
CAST/EiJ MGP_CASTEiJ_G0030376
protein coding gene Chr6:127427758-127435539 (-)
CBA/J MGP_CBAJ_G0030956
protein coding gene Chr6:137063644-137074339 (-)
DBA/2J MGP_DBA2J_G0031112
protein coding gene Chr6:122693122-122701178 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0031192
protein coding gene Chr6:128782914-128791809 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031100
protein coding gene Chr6:141103439-141111180 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031763
protein coding gene Chr6:127046497-127056013 (-)
PWK/PhJ MGP_PWKPhJ_G0030091
protein coding gene Chr6:120941210-120948996 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029920
protein coding gene Chr6:125124468-125132214 (-)
WSB/EiJ MGP_WSBEiJ_G0030461
protein coding gene Chr6:127420077-127427845 (-)



Homology
more
  • Human Ortholog
    TUBA3E, tubulin alpha 3e
  • Vertebrate Orthologs
    11
  • Human Ortholog
    TUBA3E, tubulin alpha 3e
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 112714
    neXtProt AC: NX_Q6PEY2
    UniProt: Q6PEY2

  • Chr Location
    2q21.1; chr2:130191745-130198461 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22144 NCBI Gene Model | MGI Sequence Detail 7769 C57BL/6J ±  kb
transcript NM_009446 RefSeq | MGI Sequence Detail 1552 C57BL/6  
polypeptide NP_033472 RefSeq | MGI Sequence Detail 450 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 102
    cDNA 100
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:2141443
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:25928 Villasante A, et al., Six mouse alpha-tubulin mRNAs encode five distinct isotypes: testis-specific expression of two sister genes. Mol Cell Biol. 1986 Jul;6(7):2409-19
  • Latest
    J:244859 Liu W, et al., BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis. Nat Commun. 2017 Jan 27;8:14182

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory