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Sf1
Gene Detail
 Symbol
Name
ID
Sf1
splicing factor 1
MGI:1095403
Synonyms CW17R, MZFM, WBP4, Zfp162
Feature Type protein coding gene
Genetic Map
Chromosome 19
4.48 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:6363690-6378030 bp, + strand
From VEGA annotation of GRCm38

  14341 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:134065  Vertebrate Homology Class
1 mouse; 1 rat; 1 cattle; 1 zebrafish

Gene Tree: Sf1

Alleles
and
phenotypes
All alleles(73) : Gene trapped(69) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice heterozygous for a gene trapped allele exhibit embryonic lethalilty prior to E8.5. Mice heterozygous for a gene trapped allele exhibit increased incidence of chemically induced tumors.
 
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process Leydig cell differentiation, male sex determination, ...
Component cytoplasm, nucleus, ...
Function metal ion binding, nucleic acid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (12 records)
Data Summary: Results (125)    Tissues (89)    Images (22)
Theiler Stages: 2, 3, 4, 5, 15, 17, 19, 20, 21, 22, 23, 28
Assay TypeResults
RNA in situ 104
RT-PCR 21
cDNA source data(232)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(238) Genomic(4) cDNA(232) Primer pair(2)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000018615 (Evidence)
Ensembl Gene ModelENSMUSG00000024949 (Evidence)
Entrez Gene22668 (Evidence)
UniGene256422
DFCITC1573434, TC1588263, TC1604930, TC1622081
DoTSDT.101381950, DT.101382095, DT.101382097, DT.102558061, DT.110881366, DT.535617
NIA Mouse Gene IndexU038689
Consensus CDS ProjectCCDS50368.1, CCDS50369.1
International Mouse Knockout Project StatusSf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018615 VEGA Gene Model | MGI Sequence Detail 14341 C57BL/6J ±  kb
transcript OTTMUST00000044802 VEGA | MGI Sequence Detail 4353 Not Applicable 
polypeptide OTTMUSP00000020161 VEGA | MGI Sequence Detail 639 Not Applicable 

For the selected sequences
All sequences(123) RefSeq(20) UniProt(13)
Polymorphisms SNPs within 2kb(51 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004087 K Homology domain
InterPro IPR004088 K Homology domain, type 1
InterPro IPR001878 Zinc finger, CCHC-type
Protein Ontology PR:000014730 splicing factor 1
References (Earliest) J:28401 Bettenhausen B, et al., Efficient isolation of novel mouse genes differentially expressed in early postimplantation embryos. Genomics. 1995 Aug 10;28(3):436-41
(Latest) J:191676 Manceau V, et al., The protein kinase KIS impacts gene expression during development and fear conditioning in adult mice. PLoS One. 2012;7(8):e43946
All references(52)
Other
accession IDs
MGI:2147764

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory