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Zfpm1
Gene Detail
 Symbol
Name
ID
Zfpm1
zinc finger protein, multitype 1
MGI:1095400
Synonyms Fog1, Friend of GATA-1
Feature Type protein coding gene
Genetic Map
Chromosome 8
70.86 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr8:122282141-122337251 bp, + strand
From VEGA annotation of GRCm38

  55111 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7606  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Zfpm1

Human
homologs
Human Homolog ZFPM1, zinc finger protein, FOG family member 1
NCBI Gene ID 161882
neXtProt AC  NX_Q8IX07
Human Synonyms  FOG, FOG1, ZC2HC11A, ZNF408, ZNF89A
Human Chr (Location)  16q24.2; chr16:88453606-88535166 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Targeted(7)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutants have poorly vascularized yolk sacs and small, pale livers. Mutants die between embryonic days 10.5 and 12.5 with severe anemia associated with a block in megakaryocyte development.
 
Phenotype Images(1)
Interactions
Zfpm1 interacts with 29 markers (Mir185, Mir302a, Mir302b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (54 annotations)
Process atrial septum morphogenesis, atrioventricular valve morphogenesis, ...
Component cytoplasm, nucleus, ...
Function DNA binding, metal ion binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (15 records)
Data Summary: Results (132)    Tissues (115)    Images (19)
Theiler Stages: 15, 19, 20, 21, 22, 23, 24
Assay TypeResults
RNA in situ 126
RT-PCR 6
cDNA source data(7)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(11) Genomic(1) cDNA(7) Primer pair(3)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000042121 (Evidence)
Ensembl Gene ModelENSMUSG00000049577 (Evidence)
Entrez Gene22761 (Evidence)
DFCITC1582837, TC1649157
DoTSDT.490435
NIA Mouse Gene IndexU009907
PDB1SRK
Consensus CDS ProjectCCDS22733.1
International Mouse Knockout Project StatusZfpm1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042121 VEGA Gene Model | MGI Sequence Detail 55111 C57BL/6J ±  kb
transcript OTTMUST00000110497 VEGA | MGI Sequence Detail 3390 Not Applicable 
polypeptide OTTMUSP00000061643 VEGA | MGI Sequence Detail 995 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(589 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000017652 zinc finger protein ZFPM1
References (Earliest) J:13573 LaRosa GJ, et al., Early retinoic acid-induced F9 teratocarcinoma stem cell gene ERA-1: alternate splicing creates transcripts for a homeobox-containing protein and one lacking the homeobox. Mol Cell Biol. 1988 Sep;8(9):3906-17
(Latest) J:211132 Zheng R, et al., Function of GATA factors in the adult mouse liver. PLoS One. 2013;8(12):e83723
All references(63)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory