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Abcb7
Gene Detail
Symbol

Name
ID
Abcb7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
MGI:109533
Synonyms
Abc7
Feature Type
protein coding gene
Genetic Map
Chromosome X
46.58 cM, cytoband C-D
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
ChrX:104280657-104413856 bp, - strand
From VEGA annotation of GRCm38

  133200 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3175  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: ATP-binding cassette sub-family B member 7, mitochondrial precurso
Gene Tree: Abcb7

Human
homologs
Human Homolog ABCB7, ATP-binding cassette, sub-family B (MDR/TAP), member 7
NCBI Gene ID 22
neXtProt AC  NX_O75027
Human Synonyms  ABC7, ASAT, Atm1p, EST140535
Human Chr (Location)  Xq13.3; chrX:75053172-75156340 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human ABCB7
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from APF )
 
Hemizygous male and heterozygous female mice carrying a maternally inherited null allele display prenatal lethality.
 
Interactions
Abcb7 interacts with 385 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (157)    Tissues (143)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 136
Northern blot 21
cDNA source data(19)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(20) cDNA(19) Other(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000018115 (Evidence)
Ensembl Gene ModelENSMUSG00000031333 (Evidence)
Entrez Gene11306 (Evidence)
DFCITC1629218, TC1597695
DoTSDT.111021630, DT.111021629, DT.101350064, DT.481749, DT.99850195, DT.91421222
NIA Mouse Gene IndexU039608
Consensus CDS ProjectCCDS53167.1
International Mouse Knockout Project StatusAbcb7
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018115 VEGA Gene Model | MGI Sequence Detail 133200 C57BL/6J ±  kb
transcript OTTMUST00000043710 VEGA | MGI Sequence Detail 5667 Not Applicable 
polypeptide OTTMUSP00000019632 VEGA | MGI Sequence Detail 752 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(297 from dbSNP Build 137)    SNPs within 2kb including multiple locations(309)
Protein-related
information
ResourceIDDescription
InterPro IPR003593 AAA+ ATPase domain
InterPro IPR017871 ABC transporter, conserved site
InterPro IPR003439 ABC transporter-like
InterPro IPR001140 ABC transporter, transmembrane domain
InterPro IPR011527 ABC transporter, transmembrane domain, type 1
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000003552 ATP-binding cassette sub-family B member 7, mitochondrial
References
(Earliest) J:39831 Savary S, et al., Isolation and chromosomal mapping of a novel ATP-binding cassette transporter conserved in mouse and human. Genomics. 1997 Apr 15;41(2):275-8
(Latest) J:171449 Williams LH, et al., Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass. Development. 2011 May;138(10):2049-57
All references(43)
Other
accession IDs
MGD-MRK-39532, MGI:2147832, MGI:2147959

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory