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Btg3 Gene Detail
Summary
  • Symbol
    Btg3
  • Name
    B cell translocation gene 3
  • Synonyms
    ANA, tob5
  • Feature Type
    protein coding gene
  • IDs
    MGI:109532
    NCBI Gene: 12228
  • Gene Overview
    MyGene.info: BTG3
Location & Maps
more
  • Sequence Map
    Chr16:78359860-78377192 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      17333 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 45.36 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    BTG3, BTG anti-proliferation factor 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    BTG3, BTG anti-proliferation factor 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ANA, APRO4, TOB5, TOB55, TOFA
  • Links
    NCBI Gene ID: 10950
    neXtProt AC: NX_Q14201

  • Chr Location
    21q21.1; chr21:17593650-17612950 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 4953
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: BTG3
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    1 images
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    9
  • Gene trapped
    5
  • Targeted
    4
  • Genomic Mutations
    3 involving Btg3
  • Incidental Mutations
Mice homozygous for a knock-out allele exhibit increased incidence of lung tumors.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026522 VEGA Gene Model | MGI Sequence Detail 17333 C57BL/6J ±  kb
transcript OTTMUST00000065606 VEGA | MGI Sequence Detail 1414 Not Applicable  
polypeptide OTTMUSP00000032716 VEGA | MGI Sequence Detail 252 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    103 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 46
    Genomic 1
    cDNA 43
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-39531
References
more
  • Summaries
    All 31
    Developmental Gene Expression 9
    Diseases 1
    Gene Ontology 2
    Phenotypes 11
  • Earliest
    J:38929 Guehenneux F, et al., Cloning of the mouse BTG3 gene and definition of a new gene family (the BTG family) involved in the negative control of the cell cycle. Leukemia. 1997 Mar;11(3):370-5
  • Latest
    J:184976 Narboux-Neme N, et al., Integration of H-2Z1, a Somatosensory Cortex-Expressed Transgene, Interferes with the Expression of the Satb1 and Tbc1d5 Flanking Genes and Affects the Differentiation of a Subset of Cortical Interneurons. J Neurosci. 2012 May 23;32(21):7287-7300

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory