Sms
Gene Detail

Symbol Name ID

Sms spermine synthase MGI:109490

Synonyms

SpmST

Feature Type

protein coding gene

Genetic Map

Chromosome X

72.48 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

ChrX:157443855-157492287 bp, - strand From VEGA annotation of GRCm38   48433 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:88709  Vertebrate Homology Class
1 human; 2 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Sms

Human homologs

Human Homolog		SMS, spermine synthase
NCBI Gene ID		6611
neXtProt AC		NX_P52788
Human Synonyms		MRSR, SPMSY, SpS, SRS
Human Chr (Location)		Xp22.1; chrX:21958691-22012955 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human SMS

Alleles and phenotypes

All alleles(25) : Targeted(2) Gene trapped(23)

Gene Ontology (GO) classifications

All GO classifications: (5 annotations)

Process	metabolic process, spermine biosynthetic process, ...
Function	spermine synthase activity

External Resources: FuncBase

Expression

Literature Summary: (6 records)
Data Summary: Results (229)    Tissues (129)    Images (27)
Theiler Stages: 10, 11, 13, 15, 18, 20, 22, 23, 25, 28

Assay Type	Results
RNA in situ	203
Northern blot	17
RT-PCR	9

cDNA source data(103)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(112) Genomic(1) cDNA(104) Primer pair(7)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000019398 (Evidence)
Ensembl Gene Model	ENSMUSG00000071708 (Evidence)
Entrez Gene	20603 (Evidence)
UniGene	18652
DoTS	DT.531646, DT.91563650
Consensus CDS Project	CCDS41189.1
International Mouse Knockout Project Status	Sms

Sequences

Length	Strain/Species
genomic	OTTMUSG00000019398	VEGA Gene Model | MGI Sequence Detail	48433	C57BL/6J
transcript	OTTMUST00000046291	VEGA | MGI Sequence Detail	3717	Not Applicable
polypeptide	OTTMUSP00000020908	VEGA | MGI Sequence Detail	366	Not Applicable

All sequences(41) RefSeq(2)

Polymorphisms

SNPs(204 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
Protein Ontology	PR:000015301	spermine synthase

References

(Earliest) J:38621 Strom TM, et al., Pex gene deletions in Gy and Hyp mice provide mouse models for X-linked hypophosphatemia. Hum Mol Genet. 1997 Feb;6(2):165-71
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)

Other accession IDs

MGD-MRK-39489, MGI:2147883