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Wnt8b Gene Detail
Summary
  • Symbol
    Wnt8b
  • Name
    wingless-type MMTV integration site family, member 8B
  • Feature Type
    protein coding gene
  • IDs
    MGI:109485
    NCBI Gene: 22423
  • Gene Overview
    MyGene.info: WNT8B
Location & Maps
more
  • Sequence Map
    Chr19:44493472-44514273 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      20802 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 37.98 cM
  • Mapping Data
    7 experiments
Homology
more
  • Human Ortholog
    WNT8B, Wnt family member 8B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    WNT8B, Wnt family member 8B
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 7479
    neXtProt AC: NX_Q93098

  • Chr Location
    10q24; chr10:100463055-100483642 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotype references
Mice homozygous for a null allele are viable and healthy with no evidence of hippocampal or hypothalamic defects and normal cell proliferation in the neurogenic region of the adult dentate gyrus.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 22423 NCBI Gene Model | MGI Sequence Detail 20802 C57BL/6J ±  kb
transcript NM_011720 RefSeq | MGI Sequence Detail 3376 C57BL/6  
polypeptide Q9WUD6 UniProt | EBI | MGI Sequence Detail 350 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    279 from dbSNP Build 142
  • PCR
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 36
    cDNA 24
    Primer pair 9
    Other 3

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-39484
References
more
  • Summaries
    All 117
    Developmental Gene Expression 94
    Gene Ontology 5
    Phenotypes 2
  • Earliest
    J:39203 Varlet I, et al., nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation. Development. 1997 Mar;124(5):1033-44
  • Latest
    J:231655 Barber M, et al., Migration Speed of Cajal-Retzius Cells Modulated by Vesicular Trafficking Controls the Size of Higher-Order Cortical Areas. Curr Biol. 2015 Oct 5;25(19):2466-78

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory