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Rnf103
Gene Detail
Symbol

Name
ID
Rnf103
ring finger protein 103
MGI:109483
Synonyms
kf-1, Zfp103
Feature Type
protein coding gene
Genetic Map
Chromosome 6
32.16 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:71493894-71525020 bp, + strand
From VEGA annotation of GRCm38

  31127 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4146  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RNF103
Gene Tree: Rnf103

Human
homologs
RNF103, ring finger protein 103
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 7844
neXtProt AC: NX_O00237

Human Synonyms: HKF-1, KF1, KF-1, ZFP103, ZFP-103

Human Chr (Location): 2p11.2; chr2:86603393-86623877 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(2) Spontaneous(1) Targeted(4)
Genomic Mutations involving Rnf103 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele display significantly increased anxiety-like behavior under stressful conditions as well as increased prepulse inhibition and a reduced startle amplitude with no detectable changes in exploratory locomotion or behavioral despair.
 
Interactions
Rnf103 interacts with 394 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Expression
Literature Summary: (3 records)
Data Summary: Results (58)    Tissues (48)    Images (7)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 56
RT-PCR 2
cDNA source data(41)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rnf103 ; ZFIN rnf103    NEW 
Molecular
reagents
All nucleic(44) cDNA(43) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000023991 (Evidence)
Ensembl Gene Model ENSMUSG00000052656 (Evidence)
Entrez Gene 22644 (Evidence)
UniGene 422969
DFCI TC1578700
DoTS DT.110497007, DT.94190117, DT.489348
EC 6.3.2.-
Consensus CDS Project CCDS39508.1
International Mouse Phenotyping Consortium Status Rnf103
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023991 VEGA Gene Model | MGI Sequence Detail 31127 C57BL/6J ±  kb
transcript OTTMUST00000058650 VEGA | MGI Sequence Detail 3264 Not Applicable 
polypeptide OTTMUSP00000028453 VEGA | MGI Sequence Detail 683 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(8) UniProt(4)
Polymorphisms
SNPs within 2kb(187 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
Protein Ontology PR:000014065 E3 ubiquitin-protein ligase RNF103
References
(Earliest) J:38480 Yasojima K, et al., Cloning of human and mouse cDNAs encoding novel zinc finger proteins expressed in cerebellum and hippocampus. Biochem Biophys Res Commun. 1997 Feb 13;231(2):481-7
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(39)
Other
accession IDs
MGD-MRK-39482, MGI:2141657, MGI:2141666

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory