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Usp34 Gene Detail
Summary
  • Symbol
    Usp34
  • Name
    ubiquitin specific peptidase 34
  • Synonyms
    A530081C03Rik, Murr2
  • Feature Type
    protein coding gene
  • IDs
    MGI:109473
    NCBI Gene: 17847
  • Gene Overview
    MyGene.info: USP34
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:23306895-23490560 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 14.29 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    211 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109473
protein coding gene Chr11:23306846-23490560 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018086
protein coding gene Chr11:21048700-21249579 (+)
A/J MGP_AJ_G0018059
protein coding gene Chr11:20231582-20421774 (+)
AKR/J MGP_AKRJ_G0018023
protein coding gene Chr11:20955161-21148140 (+)
BALB/cJ MGP_BALBcJ_G0018027
protein coding gene Chr11:20373250-20559837 (+)
C3H/HeJ MGP_C3HHeJ_G0017841
protein coding gene Chr11:20839113-21031388 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018479
protein coding gene Chr11:21913364-22108498 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016137
protein coding gene Chr11:19125268-19315496 (+)
CAST/EiJ MGP_CASTEiJ_G0017402
protein coding gene Chr11:20873128-21063565 (+)
CBA/J MGP_CBAJ_G0017815
protein coding gene Chr11:22873324-23093221 (+)
DBA/2J MGP_DBA2J_G0017925
protein coding gene Chr11:20162600-20347872 (+)
FVB/NJ MGP_FVBNJ_G0017917
protein coding gene Chr11:19940551-20126211 (+)
LP/J MGP_LPJ_G0017996
protein coding gene Chr11:21152570-21347341 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017943
protein coding gene Chr11:23346279-23620264 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018520
protein coding gene Chr11:21062939-21263843 (+)
PWK/PhJ MGP_PWKPhJ_G0017183
protein coding gene Chr11:20203079-20393581 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016980
protein coding gene Chr11:20822955-21014306 (+)
WSB/EiJ MGP_WSBEiJ_G0017456
protein coding gene Chr11:20701668-20899785 (+)



Homology
more
  • Human Ortholog
    USP34, ubiquitin specific peptidase 34
  • Vertebrate Orthologs
    10
  • Human Ortholog
    USP34, ubiquitin specific peptidase 34
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 9736
    neXtProt AC: NX_Q70CQ2
    UniProt: Q70CQ2

  • Chr Location
    2p15; chr2:61187455-61470714 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 40978
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: USP34
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000056342 Ensembl Gene Model | MGI Sequence Detail 183666 C57BL/6J ±  kb
transcript ENSMUST00000137823 Ensembl | MGI Sequence Detail 11363 Not Applicable  
polypeptide ENSMUSP00000120747 Ensembl | MGI Sequence Detail 3602 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • EC
  • InterPro Domains
    IPR016024 Armadillo-type fold
    IPR038765 Papain-like cysteine peptidase superfamily
    IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
    IPR018200 Ubiquitin specific protease, conserved site
    IPR028889 Ubiquitin specific protease domain
Molecular
Reagents
less
  • All nucleic 18
    Genomic 1
    cDNA 17

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-38518, MGI:2441806
References
more
  • Summaries
    All 34
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:230444 Jahan AS, et al., Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling. Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):E705-14

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory