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Ly6g Gene Detail
Summary
  • Symbol
    Ly6g
  • Name
    lymphocyte antigen 6 complex, locus G
  • Synonyms
    Gr1, Gr-1, Ly-6G
  • Feature Type
    protein coding gene
  • IDs
    MGI:109440
    NCBI Gene: 546644
  • Member of
    Ly6 cluster
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:75155261-75159128 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 34.29 cM, cytoband E1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    69 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109440
protein coding gene Chr15:75155240-75159128 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021949
protein coding gene Chr15:75047536-75049968 (+)
A/J MGP_AJ_G0021904
protein coding gene Chr15:72368052-72370478 (+)
AKR/J MGP_AKRJ_G0021888
protein coding gene Chr15:74291560-74293992 (+)
BALB/cJ MGP_BALBcJ_G0021913
protein coding gene Chr15:72357494-72359484 (+)
C3H/HeJ MGP_C3HHeJ_G0021685
protein coding gene Chr15:74393818-74398611 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022356
protein coding gene Chr15:77927632-77931517 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019888
protein coding gene Chr15:69107022-69109427 (+)
CAST/EiJ MGP_CASTEiJ_G0021207
protein coding gene Chr15:75130140-75132130 (+)
CBA/J MGP_CBAJ_G0021652
protein coding gene Chr15:80417686-80420112 (+)
DBA/2J MGP_DBA2J_G0021777
protein coding gene Chr15:71941318-71943750 (+)
FVB/NJ MGP_FVBNJ_G0021758
protein coding gene Chr15:70953622-70955618 (+)
LP/J MGP_LPJ_G0021850
protein coding gene Chr15:75150747-75153179 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021782
protein coding gene Chr15:85698747-85700737 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022377
protein coding gene Chr15:74585220-74702022 (+)
PWK/PhJ MGP_PWKPhJ_G0020948
protein coding gene Chr15:71957710-71959707 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020787
protein coding gene Chr15:74324385-74326391 (+)
WSB/EiJ MGP_WSBEiJ_G0021260
protein coding gene Chr15:74634567-74636557 (+)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    34 phenotype references
Mice homozygous for a Cre-knock-in/null allele show normal leukocyte cellularity in all measured organs. Deficient neutrophils were functionally normal in vitro and in multiple models of sterile or infectious inflammation in vivo.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 546644 NCBI Gene Model | MGI Sequence Detail 3868 C57BL/6J ±  kb
transcript NM_001310438 RefSeq | MGI Sequence Detail 922 C57BL/6  
polypeptide P35461 UniProt | EBI | MGI Sequence Detail 134 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 1
    Genomic 1

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-38485
References
more
  • Summaries
    All 93
    Developmental Gene Expression 11
    Diseases 1
    Gene Ontology 11
    Phenotypes 34
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:291976 Khatib-Massalha E, et al., Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling. Nat Commun. 2020 Jul 15;11(1):3547

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/30/2021
MGI 6.16
The Jackson Laboratory