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Ly6g Gene Detail
Summary
  • Symbol
    Ly6g
  • Name
    lymphocyte antigen 6 complex, locus G
  • Synonyms
    Gr1, Gr-1, Ly-6G
  • Feature Type
    protein coding gene
  • IDs
    MGI:109440
    NCBI Gene: 546644
  • Member of
    Ly6 cluster
Location & Maps
more
  • Sequence Map
    Chr15:75155240-75159126 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3887 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 34.29 cM, cytoband E1
  • Mapping Data
    1 experiment
Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    22 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    3
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    5 involving Ly6g
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000045113 VEGA Gene Model | MGI Sequence Detail 3887 C57BL/6J ±  kb
transcript OTTMUST00000118556 VEGA | MGI Sequence Detail 941 Not Applicable  
polypeptide OTTMUSP00000066177 VEGA | MGI Sequence Detail 134 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    69 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000002978 lymphocyte antigen 6G
  • InterPro Domains
    IPR018363 CD59 antigen, conserved site
    IPR016054 Ly-6 antigen/uPA receptor-like
Molecular
Reagents
less
  • All nucleic 1
    Genomic 1

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-38485
References
more
  • Summaries
    All 34
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 11
    Phenotypes 22
  • Earliest
    J:12607 Fleming TJ, et al., Characterization of two novel Ly-6 genes. Protein sequence and potential structural similarity to alpha-bungarotoxin and other neurotoxins. J Immunol. 1993 Jun 15;150(12):5379-90
  • Latest
    J:212190 Ge S, et al., Interleukin 17 receptor A modulates monocyte subsets and macrophage generation in vivo. PLoS One. 2014;9(1):e85461

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory