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Ly6g Gene Detail
Summary
  • Symbol
    Ly6g
  • Name
    lymphocyte antigen 6 family member G
  • Synonyms
    Gr-1, Gr1, Ly-6G
  • Feature Type
    protein coding gene
  • IDs
    MGI:109440
    NCBI Gene: 546644
  • Member of
    Ly6 cluster
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:75027110-75030977 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 34.29 cM, cytoband E1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    218 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109440
 protein coding gene Chr15:75027089-75030977 (+)
129S1/SvImJ ENSMUSG00200049368
 protein coding gene Chr15:72136285-72140170 (+)
A/J ENSMUSG00195045870
 protein coding gene Chr15:72133069-72136990 (+)
AKR/J ENSMUSG00220045791
 protein coding gene Chr15:72124745-72128631 (+)
BALB/cJ ENSMUSG00180046673
 protein coding gene Chr15:71966629-71970548 (+)
C3H/HeJ ENSMUSG00175050146
 protein coding gene Chr15:72328527-72332446 (+)
C57BL/6NJ ENSMUSG00215050582
 protein coding gene Chr15:72033819-72037704 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019888
 protein coding gene Chr15:69107022-69109427 (+)
CAST/EiJ ENSTCUG00005036512
 protein coding gene Chr15:71655093-71659035 (+)
CBA/J ENSMUSG00210042612
 protein coding gene Chr15:72103864-72107785 (+)
DBA/2J ENSMUSG00185050650
 protein coding gene Chr15:72059293-72063178 (+)
FVB/NJ ENSMUSG00205040804
 protein coding gene Chr15:71805177-71809064 (+)
JF1/MsJ ENSUMUG00000044551
 protein coding gene Chr15:71695321-71699232 (+)
LP/J ENSMUSG00230052046
 protein coding gene Chr15:75423334-75427219 (+)
NOD/ShiLtJ ENSMUSG00190050548
 protein coding gene Chr15:72057762-72061671 (+)
NZO/HlLtJ ENSMUSG00225050387
 protein coding gene Chr15:75722602-75726513 (+)
PWK/PhJ ENSLUMG00010050789
 protein coding gene Chr15:71975174-71979123 (+)
SPRET/EiJ ENSMSPG00010041422
 protein coding gene Chr15:73695288-73699194 (+)
WSB/EiJ ENSIUOG00005049486
 protein coding gene Chr15:72108272-72112169 (+)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    90 phenotype references
Mice homozygous for a Cre-knock-in/null allele show normal leukocyte cellularity in all measured organs. Deficient neutrophils were functionally normal in vitro and in multiple models of sterile or infectious inflammation in vivo.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    621
  • Tissues
    10
  • Literature Summary
    23
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 546644 NCBI Gene Model | MGI Sequence Detail 3868 C57BL/6J ±  kb
transcript NM_001310438 RefSeq | MGI Sequence Detail 922 C57BL/6  
polypeptide P35461 UniProt | EBI | MGI Sequence Detail 134 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    Genomic 1
    Primer pair 1
    Antibodies 3

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-38485
References
more
  • Summaries
    All 166
    Developmental Gene Expression 23
    Diseases 1
    Gene Ontology 13
    Phenotypes 90
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:391570 Pei S, et al., Neutrophil regulation of immunotherapy for cancer is controlled by type II interferon. Immunity. 2026 Jun 15;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory