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Ccrn4l
Gene Detail
Symbol

Name
ID
Ccrn4l
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
MGI:109382
Synonyms
Ccr4, nocturnin
Feature Type
protein coding gene
Genetic Map
Chromosome 3
22.12 cM, cytoband B-D
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:51224447-51251644 bp, + strand
From VEGA annotation of GRCm38

  27198 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7661  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Ccrn4l

Human
homologs
Human Homolog CCRN4L, CCR4 carbon catabolite repression 4-like (S. cerevisiae)
NCBI Gene ID 25819
neXtProt AC  NX_Q9UK39
Human Synonyms  Ccr4c, CCR4L, NOC
Human Chr (Location)  4q31.1; chr4:139015759-139045939 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(48) : Gene trapped(45) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele are resistant to diet-induced obesity and fatty liver development, show increased circulating glucose levels and increased insulin sensitivity on a standard diet and have impaired glucose tolerance on a high fat diet.
 
Phenotype Images(1)
Interactions
Ccrn4l interacts with 168 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (153)    Tissues (124)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 137
RT-PCR 16
cDNA source data(22)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(26) cDNA(23) Primer pair(3)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000027519 (Evidence)
Ensembl Gene ModelENSMUSG00000023087 (Evidence)
Entrez Gene12457 (Evidence)
DoTSDT.101337642, DT.97375429, DT.91399209
NIA Mouse Gene IndexU003212
EC3.1.13.4
Consensus CDS ProjectCCDS17336.1
International Mouse Knockout Project StatusCcrn4l
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027519 VEGA Gene Model | MGI Sequence Detail 27198 C57BL/6J ±  kb
transcript OTTMUST00000068124 VEGA | MGI Sequence Detail 3059 Not Applicable 
polypeptide OTTMUSP00000034381 VEGA | MGI Sequence Detail 429 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(6) UniProt(5)
Polymorphisms
SNPs within 2kb(261 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005135 Endonuclease/exonuclease/phosphatase
Protein Ontology PR:000005146 nocturnin
References
(Earliest) J:38802 Puech A, et al., Characterization of two age-induced intracisternal A-particle-related transcripts in the mouse liver. Transcriptional read-through into an open reading frame with similarities to the yeast ccr4 transcription factor. J Biol Chem. 1997 Feb 28;272(9):5995-6003
(Latest) J:201137 Zhou K, et al., Actin-related protein2/3 complex regulates tight junctions and terminal differentiation to promote epidermal barrier formation. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):E3820-E3829
All references(46)
Other
accession IDs
MGD-MRK-38427, MGI:2139914

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory