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Ell
Gene Detail
 Symbol
Name
ID
Ell
elongation factor RNA polymerase II
MGI:109377
Synonyms eleven-nineteen lysine-rich leukemia gene, Ell1, Men
Feature Type protein coding gene
Genetic Map
Chromosome 8
34.15 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:70539675-70592858 bp, + strand
From NCBI annotation of GRCm38

  53184 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4762  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Ell

Human
homologs
Human Homolog ELL, elongation factor RNA polymerase II
NCBI Gene ID 8178
neXtProt AC  NX_P55199
Human Synonyms  C19orf17, ELL1, MEN, PPP1R68
Human Chr (Location)  19p13.1; chr19:18442663-18522127 (-)  GRCh38
Alleles
and
phenotypes
All alleles(33) : Gene trapped(30) Targeted(3)
Incidental mutations (data from APF )
 
Mice homozygous for a knock-out allele die prior to E6.5 but after implantation.
 
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process in utero embryonic development, negative regulation of phosphatase activity, ...
Component nuclear speck, nucleus, ...
Function phosphatase binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (29)    Tissues (18)    Images (7)
Theiler Stages: 11, 15, 22, 24, 28
Assay TypeResults
RNA in situ 13
Northern blot 16
cDNA source data(77)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(77) cDNA(77)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000070002 (Evidence)
Entrez Gene13716 (Evidence)
UniGene271973
DFCITC1575741
DoTSDT.489899, DT.94143931
NIA Mouse Gene IndexU009433
Consensus CDS ProjectCCDS22372.1
International Mouse Knockout Project StatusEll
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 13716 NCBI Gene Model | MGI Sequence Detail 53184 C57BL/6J ±  kb
transcript NM_007924 RefSeq | MGI Sequence Detail 3085 C57BL/6 
polypeptide O08856 UniProt | EBI | MGI Sequence Detail 602 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(188 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010844 Occludin/RNA polymerase II elongation factor, ELL domain
InterPro IPR019464 RNA polymerase II elongation factor ELL
Protein Ontology PR:000007028 RNA polymerase II elongation factor ELL
Graphical View of Protein Domain Structure
References (Earliest) J:38608 Thirman MJ, et al., Developmental analysis and subcellular localization of the murine homologue of ELL. Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1408-13
(Latest) J:201955 Mourgues S, et al., ELL, a novel TFIIH partner, is involved in transcription restart after DNA repair. Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17927-32
All references(35)
Other
accession IDs
MGD-MRK-38422

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory