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Fut1
Gene Detail
Symbol

Name
ID
Fut1
fucosyltransferase 1
MGI:109375
Synonyms
H transferase
Feature Type
protein coding gene
Genetic Map
Chromosome 7
29.39 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr7:45617606-45621059 bp, + strand
From Ensembl annotation of GRCm38

  3454 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:120  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog

Gene Tree: Fut1

Human
homologs
Human Homolog FUT1, fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
NCBI Gene ID 2523
neXtProt AC  NX_P19526
Human Synonyms  H, HH, HSC
Human Chr (Location)  19q13.3; chr19:48748011-48755390 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice are viable and healthy, lack alpha(1,2)fucose residues from the apical surface of pancreatic acinar glands and are deficient in epididymal cell surface alpha(1,2)fucosylated glycans but show normal male fertility.
 
Interactions
Fut1 interacts with 173 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process fucosylation, L-fucose catabolic process, ...
Function galactoside 2-alpha-L-fucosyltransferase activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(6)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) Genomic(4) cDNA(6) Primer pair(1)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000008461 (Evidence)
Entrez Gene14343 (Evidence)
DFCITC1768520, TC1589554
DoTSDT.91360740, DT.111016370
NIA Mouse Gene IndexU008082
EC2.4.1.69
Consensus CDS ProjectCCDS21254.1
International Mouse Knockout Project StatusFut1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000008461 Ensembl Gene Model | MGI Sequence Detail 3454 C57BL/6J ±  kb
transcript ENSMUST00000008605 Ensembl | MGI Sequence Detail 2580 Not Applicable 
polypeptide ENSMUSP00000008605 Ensembl | MGI Sequence Detail 377 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(7) UniProt(4)
Polymorphisms
RFLP(1) : SNPs within 2kb(38 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002516 Glycosyl transferase, family 11
Protein Ontology PR:000007702 galactoside 2-alpha-L-fucosyltransferase 1
References
(Earliest) J:43607 Domino SE, et al., Molecular cloning, chromosomal assignment and tissue-specific expression of a murine alpha(1,2)fucosyltransferase expressed in thymic and epididymal epithelial cells. Biochem J. 1997 Oct 1;327(Pt 1):105-15
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)
Other
accession IDs
MGD-MRK-38420

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory