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Hp1bp3
Gene Detail
Symbol

Name
ID
Hp1bp3
heterochromatin protein 1, binding protein 3
MGI:109369
Synonyms
Hp1bp74, MGC:28927
Feature Type
protein coding gene
Genetic Map
Chromosome 4
70.03 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:138216296-138244683 bp, + strand
From VEGA annotation of GRCm38

  28388 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7774  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Hp1bp3

Human
homologs
Human Homolog HP1BP3, heterochromatin protein 1, binding protein 3
NCBI Gene ID 50809
neXtProt AC  NX_Q5SSJ5
Human Synonyms  HP1BP74, HP1-BP74
Human Chr (Location)  1p36.12; chr1:20742678-20787315 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(25) : Gene trapped(24) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Hp1bp3 interacts with 333 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cellular response to hypoxia, heterochromatin organization, ...
Component chromosome, nucleosome, ...
Function DNA binding, nucleosome binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(18)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(18) cDNA(18)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000009979 (Evidence)
Ensembl Gene ModelENSMUSG00000028759 (Evidence)
Entrez Gene15441 (Evidence)
DFCITC1573547, TC1653587, TC1651470, TC1626781, TC1607546, TC1678855
NIA Mouse Gene IndexU004994
Consensus CDS ProjectCCDS38927.1, CCDS51334.1
International Mouse Knockout Project StatusHp1bp3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009979 VEGA Gene Model | MGI Sequence Detail 28388 C57BL/6J ±  kb
transcript OTTMUST00000023193 VEGA | MGI Sequence Detail 5155 Not Applicable 
polypeptide OTTMUSP00000010588 VEGA | MGI Sequence Detail 554 Not Applicable 

For the selected sequences
All sequences(127) RefSeq(26) UniProt(17)
Polymorphisms
SNPs within 2kb(280 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005818 Histone H1/H5
InterPro IPR005819 Histone H5
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
Protein Ontology PR:000008726 heterochromatin protein 1-binding protein 3
References
(Earliest) J:37212 Le Douarin B, et al., A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors. EMBO J. 1996 Dec 2;15(23):6701-15
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)
Other
accession IDs
MGD-MRK-38414

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory