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Gimap1 Gene Detail
Summary
  • Symbol
    Gimap1
  • Name
    GTPase, IMAP family member 1
  • Synonyms
    38kDa, IAP38, imap, Imap38
  • Feature Type
    protein coding gene
  • IDs
    MGI:109368
    NCBI Gene: 16205
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:48739054-48743795 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 23.69 cM, cytoband B
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    33 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109368
protein coding gene Chr6:48739047-48743795 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030710
protein coding gene Chr6:47696451-47701189 (+)
A/J MGP_AJ_G0030681
protein coding gene Chr6:45530512-45536152 (+)
AKR/J MGP_AKRJ_G0030606
protein coding gene Chr6:47129348-47134080 (+)
BALB/cJ MGP_BALBcJ_G0030691
protein coding gene Chr6:45862581-45867460 (+)
C3H/HeJ MGP_C3HHeJ_G0030404
protein coding gene Chr6:47138707-47143365 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031146
protein coding gene Chr6:48817744-48822440 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028353
protein coding gene Chr6:43159056-43162594 (+)
CAST/EiJ MGP_CASTEiJ_G0029808
protein coding gene Chr6:46860961-46865764 (+)
CBA/J MGP_CBAJ_G0030379
protein coding gene Chr6:50839042-50844510 (+)
DBA/2J MGP_DBA2J_G0030528
protein coding gene Chr6:45447199-45451902 (+)
FVB/NJ MGP_FVBNJ_G0030480
protein coding gene Chr6:45080724-45085458 (+)
LP/J MGP_LPJ_G0030613
protein coding gene Chr6:47675772-47681783 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030514
protein coding gene Chr6:53652147-53658062 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031175
protein coding gene Chr6:46997016-47002759 (+)
PWK/PhJ MGP_PWKPhJ_G0029520
protein coding gene Chr6:44978946-44984131 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029356
protein coding gene Chr6:46343191-46347907 (+)
WSB/EiJ MGP_WSBEiJ_G0029885
protein coding gene Chr6:46998253-47002990 (+)



Homology
more
  • Human Ortholog
    GIMAP1, GTPase, IMAP family member 1
  • Vertebrate Orthologs
    7
  • Human Ortholog
    GIMAP1, GTPase, IMAP family member 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HIMAP1, IAN2, IMAP1, IMAP38
  • Links
    NCBI Gene ID: 170575
    neXtProt AC: NX_Q8WWP7
    UniProt: Q8WWP7

  • Chr Location
    7q36.1; chr7:150716557-150724280 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    18 phenotypes from 2 alleles in 2 genetic backgrounds
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele have defects in the development of mature B and T lymphocytes.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000090019 Ensembl Gene Model | MGI Sequence Detail 4742 C57BL/6J ±  kb
transcript ENSMUST00000054368 Ensembl | MGI Sequence Detail 1493 Not Applicable  
polypeptide ENSMUSP00000062108 Ensembl | MGI Sequence Detail 300 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    Genomic 1
    cDNA 16

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-38413
References
more
  • Summaries
    All 30
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:38420 Krucken J, et al., Novel gene expressed in spleen cells mediating acquired testosterone-resistant immunity to Plasmodium chabaudi malaria. Biochem Biophys Res Commun. 1997 Jan 3;230(1):167-70
  • Latest
    J:247251 Datta P, et al., Survival of mature T cells in the periphery is intrinsically dependent on GIMAP1 in mice. Eur J Immunol. 2017 Jan;47(1):84-93

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory