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Krt86
Gene Detail
Symbol

Name
ID
Krt86
keratin 86
MGI:109362
Synonyms
Khb4, Krt2-10, Krt2-11, MHb4
Feature Type
protein coding gene
Genetic Map
Chromosome 15
56.90 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:101473478-101479983 bp, + strand
From NCBI annotation of GRCm38

  6506 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1717  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog

Gene Tree: Krt86

Human
homologs
Human Homolog KRT86, keratin 86
NCBI Gene ID 3892
neXtProt AC  NX_O43790
Human Synonyms  Hb1, HB6, hHb6, KRTHB1, KRTHB6, MNX
Human Chr (Location)  12q13; chr12:52274651-52309163 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human KRT86
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Radiation induced(1) Targeted(1)
Genomic Mutations involving Krt86 (2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Krt86 interacts with 54 markers (Mir7-2, Mir7b, Mir16-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Component extracellular space, extracellular vesicular exosome, ...
Function structural molecule activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(10)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(19) Genomic(9) cDNA(10)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000067614 (Evidence)
Entrez Gene16679 (Evidence)
DoTSDT.101359043, DT.110836068, DT.91356355
Consensus CDS ProjectCCDS37218.1
International Mouse Knockout Project StatusKrt86
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 16679 NCBI Gene Model | MGI Sequence Detail 6506 C57BL/6J ±  kb
transcript NM_010667 RefSeq | MGI Sequence Detail 1960 C57BL/6 
polypeptide P97861 UniProt | EBI | MGI Sequence Detail 486 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(43 from dbSNP Build 137)    SNPs within 2kb including multiple locations(49)
Protein-related
information
ResourceIDDescription
InterPro IPR009030 Insulin-like growth factor binding protein, N-terminal
InterPro IPR001664 Intermediate filament protein
InterPro IPR018039 Intermediate filament protein, conserved site
InterPro IPR003054 Type II keratin
Protein Ontology PR:000009502 keratin, type II cuticular Hb6
Graphical View of Protein Domain Structure
References
(Earliest) J:22955 Knapp B, et al., Nonepidermal members of the keratin multigene family: cDNA sequences and in situ localization of the mRNAs. Nucleic Acids Res. 1986 Jan 24;14(2):751-63
(Latest) J:198837 Cui CY, et al., Frizzled6 deficiency disrupts the differentiation process of nail development. J Invest Dermatol. 2013 Aug;133(8):1990-7
All references(29)
Other
accession IDs
MGD-MRK-38407, MGI:2145983

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory