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Snap23 Gene Detail
Summary
  • Symbol
    Snap23
  • Name
    synaptosomal-associated protein 23
  • Synonyms
    SNAP-23, Sndt, Syndet
  • Feature Type
    protein coding gene
  • IDs
    MGI:109356
    NCBI Gene: 20619
  • Gene Overview
    MyGene.info: SNAP23
Location & Maps
more
  • Sequence Map
    Chr2:120567671-120601255 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      33585 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 60.37 cM, cytoband E5
  • Mapping Data
    7 experiments
Homology
more
  • Human Ortholog
    SNAP23, synaptosome associated protein 23
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SNAP23, synaptosome associated protein 23
    Orthology source: HomoloGene
  • Synonyms
    HsT17016, SNAP-23, SNAP23A, SNAP23B
  • Links
    NCBI Gene ID: 8773
    neXtProt AC: NX_O00161

  • Chr Location
    15q14; chr15:42491244-42533061 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    55
  • Chemically induced (other)
    1
  • Gene trapped
    45
  • Radiation induced
    1
  • Targeted
    8
  • Genomic Mutations
    2 involving Snap23
Mice homozygous for a knock-out allele exhibit lethality prior to E3.5.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015619 VEGA Gene Model | MGI Sequence Detail 33585 C57BL/6J ±  kb
transcript OTTMUST00000037102 VEGA | MGI Sequence Detail 2730 Not Applicable  
polypeptide OTTMUSP00000016634 VEGA | MGI Sequence Detail 221 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    163 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000015311 synaptosomal-associated protein 23
  • InterPro Domains
    IPR000928 SNAP-25
    IPR000727 Target SNARE coiled-coil homology domain
Molecular
Reagents
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  • All nucleic 15
    Genomic 1
    cDNA 13
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
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MGD-MRK-38401, MGI:2138756
References
more
  • Summaries
    All 56
    Developmental Gene Expression 3
    Gene Ontology 9
    Phenotypes 14
  • Earliest
    J:38843 Wang G, et al., Syndet is a novel SNAP-25 related protein expressed in many tissues. J Cell Sci. 1997 Feb;110(Pt 4):505-13
  • Latest
    J:226202 Kaul S, et al., Expression of the SNARE protein SNAP-23 is essential for cell survival. PLoS One. 2015;10(2):e0118311

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory