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Snap23 Gene Detail
Summary
  • Symbol
    Snap23
  • Name
    synaptosomal-associated protein 23
  • Synonyms
    SNAP-23, Sndt, Syndet
  • Feature Type
    protein coding gene
  • IDs
    MGI:109356
    NCBI Gene: 20619
  • Gene Overview
    MyGene.info: SNAP23
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:120567671-120601255 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 60.37 cM, cytoband E5
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    163 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109356
protein coding gene Chr2:120567653-120601255 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026369
protein coding gene Chr2:123434416-123468817 (+)
A/J MGP_AJ_G0026330
protein coding gene Chr2:118384538-118418877 (+)
AKR/J MGP_AKRJ_G0026309
protein coding gene Chr2:121687075-121722973 (+)
BALB/cJ MGP_BALBcJ_G0026343
protein coding gene Chr2:118622060-118655793 (+)
C3H/HeJ MGP_C3HHeJ_G0026089
protein coding gene Chr2:122178016-122214127 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026790
protein coding gene Chr2:127460318-127497042 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024170
protein coding gene Chr2:113398341-113433426 (+)
CAST/EiJ MGP_CASTEiJ_G0025551
protein coding gene Chr2:122477952-122516408 (+)
CBA/J MGP_CBAJ_G0026065
protein coding gene Chr2:131922550-131959588 (+)
DBA/2J MGP_DBA2J_G0026204
protein coding gene Chr2:117774382-117810711 (+)
FVB/NJ MGP_FVBNJ_G0026166
protein coding gene Chr2:116609615-116643033 (+)
LP/J MGP_LPJ_G0026305
protein coding gene Chr2:123700364-123734649 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026185
protein coding gene Chr2:136228575-136268110 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026845
protein coding gene Chr2:121817988-121853705 (+)
PWK/PhJ MGP_PWKPhJ_G0025287
protein coding gene Chr2:117378339-117412916 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025086
protein coding gene Chr2:120999019-121057830 (+)
WSB/EiJ MGP_WSBEiJ_G0025620
protein coding gene Chr2:122649465-122683306 (+)



Homology
more
  • Human Ortholog
    SNAP23, synaptosome associated protein 23
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SNAP23, synaptosome associated protein 23
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HsT17016, SNAP-23, SNAP23A, SNAP23B
  • Links
    NCBI Gene ID: 8773
    neXtProt AC: NX_O00161
    UniProt: O00161

  • Chr Location
    15q15.1-q15.2; chr15:42491244-42533061 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 37857
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SNAP23
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    55
  • Chemically induced (other)
    1
  • Gene trapped
    45
  • Radiation induced
    1
  • Targeted
    8
  • Genomic Mutations
    2 involving Snap23
  • Find Mice (IMSR)
Mice homozygous for a knock-out allele exhibit lethality prior to E3.5.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027287 Ensembl Gene Model | MGI Sequence Detail 33585 C57BL/6J ±  kb
transcript ENSMUST00000116437 Ensembl | MGI Sequence Detail 2730 Not Applicable  
polypeptide ENSMUSP00000112138 Ensembl | MGI Sequence Detail 221 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    Genomic 1
    cDNA 14
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-38401, MGI:2138756
References
more
  • Summaries
    All 67
    Developmental Gene Expression 4
    Gene Ontology 13
    Phenotypes 14
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:263474 Geerts CJ, et al., Tomosyn-2 is required for normal motor performance in mice and sustains neurotransmission at motor endplates. Brain Struct Funct. 2015 Jul;220(4):1971-82

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory