About   Help   FAQ
Lad1
Gene Detail
Symbol

Name
ID
Lad1
ladinin
MGI:109343
Feature Type
protein coding gene
Genetic Map
Chromosome 1
59.30 cM, cytoband E4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:135818598-135833342 bp, + strand
From VEGA annotation of GRCm38

  14745 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4059  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

HCOP human homology predictions: LAD1
Protein SuperFamily: ladinin 1
Gene Tree: Lad1

Human
homologs
LAD1, ladinin 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 3898
neXtProt AC: NX_O00515

Human Synonyms: LadA

Human Chr (Location): 1q25.1-q32.3; chr1:201380838-201399541 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
Incidental mutations (data from CvDC )
Interactions
Lad1 interacts with 145 markers (Mir17, Mir20b, Mir24-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Component basement membrane, extracellular exosome, ...
Function structural molecule activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (101)    Tissues (16)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 101
cDNA source data(73)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase lad1 ; ZFIN lad1    NEW 
Molecular
reagents
All nucleic(75) Genomic(2) cDNA(73)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000049829 (Evidence)
Ensembl Gene Model ENSMUSG00000041782 (Evidence)
Entrez Gene 16763 (Evidence)
UniGene 36726
DFCI TC1578649
DoTS DT.101248606, DT.91334827, DT.94197891
NIA Mouse Gene Index U000846
Consensus CDS Project CCDS35723.1
International Mouse Phenotyping Consortium Status Lad1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049829 VEGA Gene Model | MGI Sequence Detail 14745 C57BL/6J ±  kb
transcript OTTMUST00000126897 VEGA | MGI Sequence Detail 2993 Not Applicable 
polypeptide OTTMUSP00000068587 VEGA | MGI Sequence Detail 528 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(134 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017404 Ladinin 1
Protein Ontology PR:000009648 ladinin-1
References
(Earliest) J:38413 Motoki K, et al., Cloning and chromosomal mapping of mouse ladinin, a novel basement membrane zone component. Genomics. 1997 Feb 1;39(3):323-30
(Latest) J:220468 Walentin K, et al., A Grhl2-dependent gene network controls trophoblast branching morphogenesis. Development. 2015 Mar 15;142(6):1125-36
All references(24)
Other
accession IDs
MGD-MRK-38388

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/25/2015
MGI 6.0
The Jackson Laboratory