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Rap1gap Gene Detail
Summary
  • Symbol
    Rap1gap
  • Name
    Rap1 GTPase-activating protein
  • Synonyms
    1300019I11Rik, 2310004O14Rik, Gap, Rap1ga1
  • Feature Type
    protein coding gene
  • IDs
    MGI:109338
    NCBI Gene: 110351
  • Gene Overview
    MyGene.info: RAP1GAP
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    Chr4:137664726-137729861 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      65136 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 70.02 cM, cytoband D3
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    RAP1GAP, RAP1 GTPase activating protein
  • Vertebrate Orthologs
    8
  • Human Ortholog
    RAP1GAP, RAP1 GTPase activating protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RAP1GA1, RAP1GAP1, RAP1GAPII, RAPGAP
  • Links
    NCBI Gene ID: 5909
    neXtProt AC: NX_P47736
    UniProt: P47736

  • Chr Location
    1p36.12; chr1:21596215-21669444 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    189
  • Tissues
    27
  • cDNA Data
    81
  • Literature Summary
    6
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009739 VEGA Gene Model | MGI Sequence Detail 65136 C57BL/6J ±  kb
transcript OTTMUST00000022502 VEGA | MGI Sequence Detail 4140 Not Applicable  
polypeptide OTTMUSP00000010269 VEGA | MGI Sequence Detail 729 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    798 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 83
    cDNA 81
    Other 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-38383, MGI:1923530, MGI:1926025, MGI:2140268
References
more
  • Summaries
    All 40
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:37223 Gould KA, et al., Genetic evaluation of candidate genes for the Mom1 modifier of intestinal neoplasia in mice. Genetics. 1996 Dec;144(4):1777-85
  • Latest
    J:226997 Bebee TW, et al., The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development. Elife. 2015;4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/10/2017
MGI 6.10 		The Jackson Laboratory