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Trim24
Gene Detail
Symbol

Name
ID
Trim24
tripartite motif-containing 24
MGI:109275
Synonyms
A130082H20Rik, D430004I05Rik, Tif1a, TIF1alpha
Feature Type
protein coding gene
Genetic Map
Chromosome 6
17.07 cM, cytoband B1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:37870811-37966296 bp, + strand
From VEGA annotation of GRCm38

  95486 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20830  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Trim24

Human
homologs
Human Homolog TRIM24, tripartite motif containing 24
NCBI Gene ID 8805
neXtProt AC  NX_O15164
Human Synonyms  hTIF1, PTC6, RNF82, TF1A, TIF1, TIF1A, TIF1ALPHA
Human Chr (Location)  7q32-q34; chr7:138460334-138585588 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human TRIM24
Mutations,
alleles, and
phenotypes
All mutations/alleles(48) : Gene trapped(44) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit increased hepatocyte ploidy and uncontrolled hepatocellular proliferation; most adult mice develop malignant hepatocellular carcinomas.
 
Interactions
Trim24 interacts with 123 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (10 records)
Data Summary: Results (189)    Tissues (121)    Images (36)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 4
RNA in situ 133
Northern blot 1
Western blot 7
RT-PCR 44
cDNA source data(130)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(137) cDNA(133) Primer pair(3) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000030316 (Evidence)
Ensembl Gene ModelENSMUSG00000029833 (Evidence)
Entrez Gene21848 (Evidence)
UniGene41063
DFCITC1669996, TC1574963, TC1653264, TC1611743, TC1607229
DoTSDT.101736780, DT.101309591, DT.94211347, DT.91572747, DT.102545940
EC6.3.2.-
Consensus CDS ProjectCCDS20008.1, CCDS71751.1, CCDS71752.1
International Mouse Knockout Project StatusTrim24
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030316 VEGA Gene Model | MGI Sequence Detail 95486 C57BL/6J ±  kb
transcript OTTMUST00000075084 VEGA | MGI Sequence Detail 4042 Not Applicable 
polypeptide OTTMUSP00000039294 VEGA | MGI Sequence Detail 1051 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(8) UniProt(9)
Polymorphisms
SNPs within 2kb(269 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003649 B-box, C-terminal
InterPro IPR001487 Bromodomain
InterPro IPR018359 Bromodomain, conserved site
InterPro IPR000315 Zinc finger, B-box
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR019787 Zinc finger, PHD-finger
InterPro IPR001965 Zinc finger, PHD-type
InterPro IPR019786 Zinc finger, PHD-type, conserved site
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
InterPro IPR017907 Zinc finger, RING-type, conserved site
Protein Ontology PR:000016649 transcription intermediary factor 1-alpha
References
(Earliest) J:30466 Miki T, et al., Development of a highly efficient expression cDNA cloning system: application to oncogene isolation. Proc Natl Acad Sci U S A. 1991 Jun 15;88(12):5167-71
(Latest) J:174767 Tang F, et al., Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
All references(60)
Other
accession IDs
MGD-MRK-38320, MGI:1889824, MGI:2442432, MGI:2445188

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory