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Zhx1 Gene Detail
Summary
  • Symbol
    Zhx1
  • Name
    zinc fingers and homeoboxes 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:109271
    NCBI Gene: 22770
  • Gene Overview
    MyGene.info: ZHX1
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr15:58047003-58076508 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 24.25 cM, cytoband D2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    100 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109271
protein coding gene Chr15:58047003-58076541 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021867
protein coding gene Chr15:57203770-57235803 (-)
A/J MGP_AJ_G0021827
protein coding gene Chr15:54959225-54988839 (-)
AKR/J MGP_AKRJ_G0021808
protein coding gene Chr15:56473761-56511936 (-)
BALB/cJ MGP_BALBcJ_G0021834
protein coding gene Chr15:55185580-55215317 (-)
C3H/HeJ MGP_C3HHeJ_G0021608
protein coding gene Chr15:56608512-56638513 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022273
protein coding gene Chr15:59434389-59466912 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019810
protein coding gene Chr15:52056967-52084842 (-)
CAST/EiJ MGP_CASTEiJ_G0021125
protein coding gene Chr15:57234235-57270629 (-)
CBA/J MGP_CBAJ_G0021577
protein coding gene Chr15:61497551-61526741 (-)
DBA/2J MGP_DBA2J_G0021701
protein coding gene Chr15:54883529-54913582 (-)
FVB/NJ MGP_FVBNJ_G0021679
protein coding gene Chr15:53937090-53967972 (-)
LP/J MGP_LPJ_G0021771
protein coding gene Chr15:57051246-57082933 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021703
protein coding gene Chr15:66572032-66603313 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022296
protein coding gene Chr15:56897602-56926933 (-)
PWK/PhJ MGP_PWKPhJ_G0020870
protein coding gene Chr15:54884025-54914620 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020707
protein coding gene Chr15:56659421-56690252 (-)
WSB/EiJ MGP_WSBEiJ_G0021180
protein coding gene Chr15:56879360-56909968 (-)



Homology
more
  • Human Ortholog
    ZHX1, zinc fingers and homeoboxes 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ZHX1, zinc fingers and homeoboxes 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 11244
    neXtProt AC: NX_Q9UKY1
    UniProt: Q9UKY1

  • Chr Location
    8q24.13; chr8:123248450-123275541 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 5225
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ZHX1
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Genomic Mutations
    4 involving Zhx1
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22770 NCBI Gene Model | MGI Sequence Detail 29506 C57BL/6J ±  kb
transcript NM_001042438 RefSeq | MGI Sequence Detail 5231 C57BL/6  
polypeptide P70121 UniProt | EBI | MGI Sequence Detail 873 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 79
    cDNA 79

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-38316
References
more
  • Summaries
    All 43
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 7
    Phenotypes 12
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory