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Zhx1 Gene Detail
Summary
  • Symbol
    Zhx1
  • Name
    zinc fingers and homeoboxes 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:109271
    NCBI Gene: 22770
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:57910399-57939904 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 24.25 cM, cytoband D2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    532 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109271
 protein coding gene Chr15:57910399-57939937 (-)
129S1/SvImJ ENSMUSG00200028957
 protein coding gene Chr15:54892959-54922447 (-)
A/J ENSMUSG00195005874
 protein coding gene Chr15:54957097-54986583 (-)
AKR/J ENSMUSG00220020540
 protein coding gene Chr15:54930905-54960767 (-)
BALB/cJ ENSMUSG00180008509
 protein coding gene Chr15:54881309-54910795 (-)
C3H/HeJ ENSMUSG00175004771
 protein coding gene Chr15:55133129-55162609 (-)
C57BL/6NJ ENSMUSG00215009600
 protein coding gene Chr15:54874437-54903923 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019810
 protein coding gene Chr15:52056967-52084842 (-)
CAST/EiJ ENSTCUG00005006708
 protein coding gene Chr15:54760879-54798676 (-)
CBA/J ENSMUSG00210006962
 protein coding gene Chr15:54956879-54986365 (-)
DBA/2J ENSMUSG00185026495
 protein coding gene Chr15:54932734-54962220 (-)
FVB/NJ ENSMUSG00205006212
 protein coding gene Chr15:54761746-54791230 (-)
JF1/MsJ ENSUMUG00000020601
 protein coding gene Chr15:54738489-54768593 (-)
LP/J ENSMUSG00230006988
 protein coding gene Chr15:58236512-58265998 (-)
NOD/ShiLtJ ENSMUSG00190016648
 protein coding gene Chr15:54942026-54971512 (-)
NZO/HlLtJ ENSMUSG00225028194
 protein coding gene Chr15:58567479-58596972 (-)
PWK/PhJ ENSLUMG00010026464
 protein coding gene Chr15:55020185-55050368 (-)
SPRET/EiJ ENSMSPG00010024019
 protein coding gene Chr15:56199691-56202614 (-)
WSB/EiJ ENSIUOG00005006002
 protein coding gene Chr15:54979798-55009660 (-)



Homology
more
  • Human Ortholog
    ZHX1, zinc fingers and homeoboxes 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZHX1, zinc fingers and homeoboxes 1
  • Links
    NCBI Gene ID: 11244
    UniProt: Q9UKY1

  • Chr Location
    8q24.13; chr8:123248451-123275541 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    2
  • Radiation induced
    1
  • Genomic Mutations
    4 involving Zhx1
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    35 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    668
  • Tissues
    60
  • cDNA Data
    82
  • Literature Summary
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22770 NCBI Gene Model | MGI Sequence Detail 29506 C57BL/6J ±  kb
transcript NM_001042438 RefSeq | MGI Sequence Detail 5231 C57BL/6  
polypeptide P70121 UniProt | EBI | MGI Sequence Detail 873 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 83
    cDNA 82
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-38316
References
more
  • Summaries
    All 55
    Developmental Gene Expression 8
    Diseases 1
    Gene Ontology 9
    Phenotypes 15
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory