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Zhx1 Gene Detail
Summary
  • Symbol
    Zhx1
  • Name
    zinc fingers and homeoboxes 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:109271
    NCBI Gene: 22770
  • Gene Overview
    MyGene.info: ZHX1
Location & Maps
more
  • Sequence Map
    Chr15:58047003-58076541 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      29539 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 24.25 cM, cytoband D2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ZHX1, zinc fingers and homeoboxes 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ZHX1, zinc fingers and homeoboxes 1
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 11244
    neXtProt AC: NX_Q9UKY1

  • Chr Location
    8q24.13; chr8:123248450-123275541 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 5225
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog
  • HCOP
    human homology predictions: ZHX1
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    3
  • Radiation induced
    1
  • Genomic Mutations
    4 involving Zhx1
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000041982 VEGA Gene Model | MGI Sequence Detail 29539 C57BL/6J ±  kb
transcript OTTMUST00000109936 VEGA | MGI Sequence Detail 4839 Not Applicable  
polypeptide OTTMUSP00000061250 VEGA | MGI Sequence Detail 873 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    100 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 78
    cDNA 78

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-38316
References
more
  • Summaries
    All 29
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:34494 Barthelemy I, et al., zhx-1: a novel mouse homeodomain protein containing two zinc-fingers and five homeodomains. Biochem Biophys Res Commun. 1996 Jul 25;224(3):870-6
  • Latest
    J:168654 Chung YC, et al., Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):84-92

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory