Gzmf
Gene Detail

Symbol Name ID

Gzmf granzyme F MGI:109254

Synonyms

CCP4, Ctla7, Ctla-7, CTL serine protease 3, granzyme G, MCSP-3

Feature Type

protein coding gene

Genetic Map

Chromosome 14

28.19 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(7)

Sequence Map

Chr14:56205266-56211407 bp, - strand From Ensembl annotation of GRCm38   6142 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:133275  Vertebrate Homology Class
4 mouse; 1 rat

Protein SuperFamily: trypsin
Gene Tree: Gzmf

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	cytolysis, proteolysis
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (10)    Tissues (4)   
Theiler Stages: 20, 22, 28

Assay Type	Results
RT-PCR	10

cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(23) Genomic(7) cDNA(12) Primer pair(2) Other(2)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000015441 (Evidence)
Entrez Gene	14943 (Evidence)
UniGene	457976
DFCI	TC1585608
DoTS	DT.531640
EC	3.4.21.-
Consensus CDS Project	CCDS36936.1
International Mouse Knockout Project Status	Gzmf

Sequences

Length	Strain/Species
genomic	ENSMUSG00000015441	Ensembl Gene Model | MGI Sequence Detail	6142	C57BL/6J
transcript	ENSMUST00000022757	Ensembl | MGI Sequence Detail	906	Not Applicable
polypeptide	ENSMUSP00000022757	Ensembl | MGI Sequence Detail	248	Not Applicable

All sequences(17) RefSeq(2) UniProt(2)

Polymorphisms

RFLP(1) : SNPs(133 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001254	Peptidase S1
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR018114	Peptidase S1, trypsin family, active site
InterPro	IPR009003	Trypsin-like cysteine/serine peptidase domain
Protein Ontology	PR:000003493	granzyme F

References

(Earliest) J:21438 Jenne D, et al., Identification and sequencing of cDNA clones encoding the granule-associated serine proteases granzymes D, E, and F of cytolytic T lymphocytes. Proc Natl Acad Sci U S A. 1988 Jul;85(13):4814-8
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(36)

Other accession IDs

MGD-MRK-2227, MGD-MRK-2237, MGD-MRK-38299