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Gzmf
Gene Detail
 Symbol
Name
ID
Gzmf
granzyme F
MGI:109254
Synonyms CCP4, Ctla7, Ctla-7, CTL serine protease 3, granzyme G, MCSP-3
Feature Type protein coding gene
Genetic Map
Chromosome 14
28.19 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr14:56205266-56211407 bp, - strand
From Ensembl annotation of GRCm38

  6142 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:133275  Vertebrate Homology Class
4 mouse; 1 rat

Protein SuperFamily: trypsin
Gene Tree: Gzmf

Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process cytolysis, proteolysis
Component secretory granule
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (10)    Tissues (4)   
Theiler Stages: 20, 22, 28
Assay TypeResults
RT-PCR 10
cDNA source data(10)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(22) Genomic(7) cDNA(11) Primer pair(2) Other(2)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000015441 (Evidence)
Entrez Gene14943 (Evidence)
UniGene457976
DFCITC1585608
DoTSDT.531640
EC3.4.21.-
Consensus CDS ProjectCCDS36936.1
International Mouse Knockout Project StatusGzmf
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000015441 Ensembl Gene Model | MGI Sequence Detail 6142 C57BL/6J ±  kb
transcript ENSMUST00000022757 Ensembl | MGI Sequence Detail 906 Not Applicable 
polypeptide ENSMUSP00000022757 Ensembl | MGI Sequence Detail 248 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(2)
Polymorphisms RFLP(1) : SNPs within 2kb(159 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000003493 granzyme F
References (Earliest) J:21438 Jenne D, et al., Identification and sequencing of cDNA clones encoding the granule-associated serine proteases granzymes D, E, and F of cytolytic T lymphocytes. Proc Natl Acad Sci U S A. 1988 Jul;85(13):4814-8
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(37)
Other
accession IDs
MGD-MRK-2227, MGD-MRK-2237, MGD-MRK-38299

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory