Gzmg
Gene Detail

Symbol Name ID

Gzmg granzyme G MGI:109253

Synonyms

Ctla7, Ctla-7

Feature Type

protein coding gene

Genetic Map

Chromosome 14

28.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr14:56156582-56159579 bp, - strand From Ensembl annotation of GRCm38   2998 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:133275  Vertebrate Homology Class
4 mouse; 1 rat

Protein SuperFamily: trypsin
Gene Tree: Gzmg

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	cytolysis, proteolysis
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (33)    Tissues (25)    Images (9)
Theiler Stages: 1, 2, 3, 4, 5, 8, 11, 15, 19, 20, 21, 23, 25, 26, 28

Assay Type	Results
Immunohistochemistry	3
RNA in situ	4
RT-PCR	26

cDNA source data(13)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(20) Genomic(2) cDNA(13) Primer pair(3) Other(2)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000040284 (Evidence)
Entrez Gene	14944 (Evidence)
UniGene	14868
DFCI	TC1585737
DoTS	DT.55274966
NIA Mouse Gene Index	U035603
EC	3.4.21.-
Consensus CDS Project	CCDS27144.1
International Mouse Knockout Project Status	Gzmg

Sequences

Length	Strain/Species
genomic	ENSMUSG00000040284	Ensembl Gene Model | MGI Sequence Detail	2998	C57BL/6J
transcript	ENSMUST00000015578	Ensembl | MGI Sequence Detail	909	Not Applicable
polypeptide	ENSMUSP00000015578	Ensembl | MGI Sequence Detail	248	Not Applicable

All sequences(16) RefSeq(2) UniProt(2)

Polymorphisms

PCR(1) : SNPs(105 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009003	Peptidase cysteine/serine, trypsin-like
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR001254	Peptidase S1/S6, chymotrypsin/Hap
InterPro	IPR018114	Peptidase S1/S6, chymotrypsin/Hap, active site
Protein Ontology	PR:000003478	granzyme G

References

(Earliest) J:39247 Masson D, et al., A family of serine esterases in lytic granules of cytolytic T lymphocytes. Cell. 1987 Jun 5;49(5):679-85
(Latest) J:163833 Tsai TC, et al., Granzyme G is expressed in the two-cell stage mouse embryo and is required for the maternal-zygotic transition. BMC Dev Biol. 2010;10:88
All references(30)

Other accession IDs

MGD-MRK-2237, MGD-MRK-38298