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Tead3 Gene Detail
Summary
  • Symbol
    Tead3
  • Name
    TEA domain family member 3
  • Synonyms
    DTEF-1, ETFR-1, Tcf13r2, TEAD-3, TEF-5
  • Feature Type
    protein coding gene
  • IDs
    MGI:109241
    NCBI Gene: 21678
  • Gene Overview
    MyGene.info: TEAD3
Location & Maps
more
  • Sequence Map
    Chr17:28331671-28350805 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19135 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 14.66 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TEAD3, TEA domain transcription factor 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TEAD3, TEA domain transcription factor 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    DTEF-1, ETFR-1, TEAD-3, TEAD5, TEF5, TEF-5
  • Links
    NCBI Gene ID: 7005
    neXtProt AC: NX_Q99594

  • Chr Location
    6p21.2; chr6:35473597-35497084 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024245 VEGA Gene Model | MGI Sequence Detail 19135 C57BL/6J ±  kb
transcript OTTMUST00000059334 VEGA | MGI Sequence Detail 2448 Not Applicable  
polypeptide OTTMUSP00000028855 VEGA | MGI Sequence Detail 465 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    51 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000016220 transcriptional enhancer factor TEF-5
  • InterPro Domains
    IPR000818 TEA/ATTS domain
    IPR016361 Transcriptional enhancer factor, metazoa
    IPR027253 Transcriptional enhancer factor TEF-5 (TEAD3)
Molecular
Reagents
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  • All nucleic 71
    Genomic 2
    cDNA 65
    Primer pair 3
    Other 1

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-38286, MGI:2147049
References
more
  • Summaries
    All 52
    Developmental Gene Expression 16
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:48110 Burglin TR, The TEA domain: a novel, highly conserved DNA-binding motif [letter]. Cell. 1991 Jul 12;66(1):11-2
  • Latest
    J:184824 Liu-Chittenden Y, et al., Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. Genes Dev. 2012 Jun 15;26(12):1300-5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory