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Tead3 Gene Detail
Summary
  • Symbol
    Tead3
  • Name
    TEA domain family member 3
  • Synonyms
    DTEF-1, ETFR-1, Tcf13r2, TEAD-3, TEF-5
  • Feature Type
    protein coding gene
  • IDs
    MGI:109241
    NCBI Gene: 21678
  • Gene Overview
    MyGene.info: TEAD3
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:28331671-28350805 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 14.66 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    51 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109241
protein coding gene Chr17:28331671-28350805 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023439
protein coding gene Chr17:27720310-27740974 (-)
A/J MGP_AJ_G0023397
protein coding gene Chr17:26813199-26832076 (-)
AKR/J MGP_AKRJ_G0023362
protein coding gene Chr17:27011493-27030370 (-)
BALB/cJ MGP_BALBcJ_G0023402
protein coding gene Chr17:27080165-27099616 (-)
C3H/HeJ MGP_C3HHeJ_G0023163
protein coding gene Chr17:27391604-27414633 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023844
protein coding gene Chr17:28840533-28853963 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021319
protein coding gene Chr17:24185490-24204236 (-)
CAST/EiJ MGP_CASTEiJ_G0022664
protein coding gene Chr17:27373308-27392289 (-)
CBA/J MGP_CBAJ_G0023137
protein coding gene Chr17:29868058-29894108 (-)
DBA/2J MGP_DBA2J_G0023268
protein coding gene Chr17:26367317-26387154 (-)
FVB/NJ MGP_FVBNJ_G0023238
protein coding gene Chr17:26176091-26203147 (-)
LP/J MGP_LPJ_G0023346
protein coding gene Chr17:27974944-27992313 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023256
protein coding gene Chr17:29306074-29325461 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023886
protein coding gene Chr17:27432217-27464463 (-)
PWK/PhJ MGP_PWKPhJ_G0022414
protein coding gene Chr17:25175764-25194598 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022232
protein coding gene Chr17:25438028-25456626 (-)
WSB/EiJ MGP_WSBEiJ_G0022726
protein coding gene Chr17:27429991-27452134 (-)



Homology
more
  • Human Ortholog
    TEAD3, TEA domain transcription factor 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TEAD3, TEA domain transcription factor 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DTEF-1, ETFR-1, TEAD-3, TEAD5, TEF5, TEF-5
  • Links
    NCBI Gene ID: 7005
    neXtProt AC: NX_Q99594
    UniProt: Q99594

  • Chr Location
    6p21.31; chr6:35473597-35497084 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 21678 NCBI Gene Model | MGI Sequence Detail 19135 C57BL/6J ±  kb
transcript NM_001204156 RefSeq | MGI Sequence Detail 2775 C57BL/6  
polypeptide P70210 UniProt | EBI | MGI Sequence Detail 439 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    6 Sequences
  • InterPro Domains
    IPR000818 TEA/ATTS domain
    IPR038096 TEA/ATTS domain superfamily
    IPR016361 Transcriptional enhancer factor, metazoa
    IPR027253 Transcriptional enhancer factor TEF-5 (TEAD3)
Molecular
Reagents
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  • All nucleic 73
    Genomic 2
    cDNA 67
    Primer pair 3
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-38286, MGI:2147049
References
more
  • Summaries
    All 57
    Developmental Gene Expression 18
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:48110 Burglin TR, The TEA domain: a novel, highly conserved DNA-binding motif [letter]. Cell. 1991 Jul 12;66(1):11-2
  • Latest
    J:244545 Peraki I, et al., The Ets2 Repressor Factor (Erf) Is Required for Effective Primitive and Definitive Hematopoiesis. Mol Cell Biol. 2017 Oct 01;37(19)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory