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Ube2l3
Gene Detail
 Symbol
Name
ID
Ube2l3
ubiquitin-conjugating enzyme E2L 3
MGI:109240
Synonyms Ubce7, UbcM4
Feature Type protein coding gene
Genetic Map
Chromosome 16
10.63 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr16:17152013-17202649 bp, - strand
From VEGA annotation of GRCm38

  50637 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:43226  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: ubiquitin-conjugating enzyme E2
Gene Tree: Ube2l3

Human
homologs
Human Homolog UBE2L3, ubiquitin-conjugating enzyme E2L 3
NCBI Gene ID 7332
neXtProt AC  NX_P68036
Human Synonyms  E2-F1, L-UBC, UBCH7, UbcM4
Human Chr (Location)  22q11.21; chr22:21549447-21624034 (+)  GRCh38
Alleles
and
phenotypes
All alleles(171) : Gene trapped(170) Transgenic(1)
 
A portion of hypomorphic embyros die before birth while those that survive are growth retarded and do not survive past the first day of life. The embryonic and perinatal lethality are attributed to defective placental development.
 
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cell proliferation, cellular response to glucocorticoid stimulus, ...
Component cytoplasm, extracellular vesicular exosome, ...
Function poly(A) RNA binding, transcription coactivator activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (55)    Tissues (19)    Images (4)
Theiler Stages: 17, 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
Northern blot 55
cDNA source data(21)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(29) Genomic(8) cDNA(21)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000025066 (Evidence)
Ensembl Gene ModelENSMUSG00000038965 (Evidence)
Entrez Gene22195 (Evidence)
DFCITC1573162
DoTSDT.101159533, DT.55101245, DT.94345283
Consensus CDS ProjectCCDS27997.1
International Mouse Knockout Project StatusUbe2l3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025066 VEGA Gene Model | MGI Sequence Detail 50637 C57BL/6J ±  kb
transcript OTTMUST00000061185 VEGA | MGI Sequence Detail 2906 Not Applicable 
polypeptide OTTMUSP00000029959 VEGA | MGI Sequence Detail 154 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(4)
Polymorphisms RFLP(1) : SNPs within 2kb(71 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000032616 ubiquitin-conjugating enzyme E2 L3
References (Earliest) J:31581 Matuschewski K, et al., Identification of a novel family of ubiquitin-conjugating enzymes with distinct amino-terminal extensions. J Biol Chem. 1996 Feb 2;271(5):2789-94
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)
Other
accession IDs
MGD-MRK-38285, MGI:2146706

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory