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Kif22
Gene Detail
Symbol

Name
ID
Kif22
kinesin family member 22
MGI:109233
Synonyms
Kid, Kif22a
Feature Type
protein coding gene
Genetic Map
Chromosome 7
69.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:127027732-127042420 bp, - strand
From Ensembl annotation of GRCm38

  14689 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32011  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: kinesin-like protein KIF22
Gene Tree: Kif22

Human
homologs
Human Homolog KIF22, kinesin family member 22
NCBI Gene ID 3835
neXtProt AC  NX_Q14807
Human Synonyms  A-328A3.2, KID, KNSL4, OBP, OBP-1, OBP-2, SEMDJL2
Human Chr (Location)  16p11.2; chr16:29790062-29805385 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human KIF22
Mutations,
alleles, and
phenotypes
All mutations/alleles(56) : Gene trapped(50) Targeted(6)
Genomic Mutations involving Kif22 (2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit embryonic lethality prior to implantation due to defective meiosis II and early embryo mitosis.
 
Alleles Annotated to Human Diseases(1)   
Interactions
Kif22 interacts with 55 markers (Mir29a, Mir29b-1, Mir29b-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process ATP catabolic process, DNA repair, ...
Component chromatin, cytoplasm, ...
Function ATPase activity, ATP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (2)    Tissues (2)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 2
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) cDNA(16)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000030677 (Evidence)
Entrez Gene110033 (Evidence)
DFCITC1601786, TC1573002
DoTSDT.94151048, DT.490483
NIA Mouse Gene IndexU029275
Consensus CDS ProjectCCDS21855.1
International Mouse Knockout Project StatusKif22
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030677 Ensembl Gene Model | MGI Sequence Detail 14689 C57BL/6J ±  kb
transcript ENSMUST00000032915 Ensembl | MGI Sequence Detail 2063 Not Applicable 
polypeptide ENSMUSP00000032915 Ensembl | MGI Sequence Detail 660 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(4) UniProt(1)
Polymorphisms
RFLP(1) : SNPs within 2kb(54 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003583 Helix-hairpin-helix DNA-binding motif, class 1
InterPro IPR026986 Kinesin-like protein KIF22 (Kid)
InterPro IPR001752 Kinesin, motor domain
InterPro IPR019821 Kinesin, motor region, conserved site
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR010994 RuvA domain 2-like
Protein Ontology PR:000009301 kinesin-like protein KIF22
References
(Earliest) J:43498 Yang Z, et al., Identification, partial characterization, and genetic mapping of kinesin-like protein genes in mouse. Genomics. 1997 Oct 1;45(1):123-31
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(43)
Other
accession IDs
MGD-MRK-38277, MGI:2142138, MGI:2142351

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory