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Kifc3 Gene Detail
Summary
  • Symbol
    Kifc3
  • Name
    kinesin family member C3
  • Feature Type
    protein coding gene
  • IDs
    MGI:109202
    NCBI Gene: 16582
  • Gene Overview
    MyGene.info: KIFC3
Location & Maps
more
  • Sequence Map
    Chr8:95099832-95142540 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      42709 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 47.12 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    KIFC3, kinesin family member C3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    KIFC3, kinesin family member C3
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 3801
    neXtProt AC: NX_Q9BVG8

  • Chr Location
    16q13-q21; chr16:57758217-57863053 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 124421
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: KIFC3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Mice homozygous for this targeted mutation are viable, fertile, and appear phenotypically indistinguishable from wild-type littermates.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031788 Ensembl Gene Model | MGI Sequence Detail 42709 C57BL/6J ±  kb
transcript ENSMUST00000034240 Ensembl | MGI Sequence Detail 3266 Not Applicable  
polypeptide ENSMUSP00000034240 Ensembl | MGI Sequence Detail 824 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    940 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000009325 kinesin-like protein KIFC3
  • InterPro Domains
    IPR027640 Kinesin-like protein
    IPR027325 Kinesin-like protein KIFC3
    IPR001752 Kinesin motor domain
    IPR019821 Kinesin motor domain, conserved site
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 76
    cDNA 75
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
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MGD-MRK-38246, MGI:2142509, MGI:2142831
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:42822 Nakagawa T, et al., Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome. Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9654-9
  • Latest
    J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory