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Kifc2 Gene Detail
Summary
  • Symbol
    Kifc2
  • Name
    kinesin family member C2
  • Feature Type
    protein coding gene
  • IDs
    MGI:109187
    NCBI Gene: 16581
Location & Maps
more
  • Sequence Map
    Chr15:76660641-76668196 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7556 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 36.23 cM, cytoband D-E
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    KIFC2, kinesin family member C2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    KIFC2, kinesin family member C2
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 90990
    neXtProt AC: NX_Q96AC6

  • Chr Location
    8q24.3; chr8:144466149-144474116 (+)  GRCh38.p2

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    26 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    3
  • Radiation induced
    2
  • Targeted
    4
  • Genomic Mutations
    5 involving Kifc2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000004187 Ensembl Gene Model | MGI Sequence Detail 7556 C57BL/6J ±  kb
transcript ENSMUST00000004294 Ensembl | MGI Sequence Detail 3143 Not Applicable  
polypeptide ENSMUSP00000004294 Ensembl | MGI Sequence Detail 792 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    24 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000009324 kinesin-like protein KIFC2
  • InterPro Domains
    IPR027640 Kinesin-like protein
    IPR001752 Kinesin motor domain
    IPR019821 Kinesin motor domain, conserved site
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 10
    cDNA 8
    Primer pair 1
    Other 1

    Microarray probesets 7
Other
Accession IDs
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MGD-MRK-38231
References
more
  • Summaries
    All 32
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 4
    Phenotypes 26
  • Earliest
    J:39083 Hanlon DW, et al., Characterization of KIFC2, a neuronal kinesin superfamily member in mouse. Neuron. 1997 Mar;18(3):439-51
  • Latest
    J:174767 Tang F, et al., Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory