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Kifc2 Gene Detail
Summary
  • Symbol
    Kifc2
  • Name
    kinesin family member C2
  • Feature Type
    protein coding gene
  • IDs
    MGI:109187
    NCBI Gene: 16581
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:76659858-76668196 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 36.23 cM, cytoband D-E
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    24 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109187
protein coding gene Chr15:76659835-76668196 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022004
protein coding gene Chr15:76754111-76761583 (+)
A/J MGP_AJ_G0021962
protein coding gene Chr15:73948048-73955354 (+)
AKR/J MGP_AKRJ_G0021945
protein coding gene Chr15:75954794-75962169 (+)
BALB/cJ MGP_BALBcJ_G0021971
protein coding gene Chr15:73973662-73980993 (+)
C3H/HeJ MGP_C3HHeJ_G0021743
protein coding gene Chr15:75999931-76007265 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022411
protein coding gene Chr15:79618666-79625936 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019940
protein coding gene Chr15:70604288-70612711 (+)
CAST/EiJ MGP_CASTEiJ_G0021262
protein coding gene Chr15:76804423-76811782 (+)
CBA/J MGP_CBAJ_G0021710
protein coding gene Chr15:82142934-82152246 (+)
DBA/2J MGP_DBA2J_G0021835
protein coding gene Chr15:73485223-73492401 (+)
FVB/NJ MGP_FVBNJ_G0021815
protein coding gene Chr15:72543192-72550537 (+)
LP/J MGP_LPJ_G0021906
protein coding gene Chr15:76842567-76851010 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021840
protein coding gene Chr15:87474392-87481711 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022431
protein coding gene Chr15:76229680-76236992 (+)
PWK/PhJ MGP_PWKPhJ_G0021003
protein coding gene Chr15:73649909-73657487 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020843
protein coding gene Chr15:75923291-75931497 (+)
WSB/EiJ MGP_WSBEiJ_G0021314
protein coding gene Chr15:76316654-76323976 (+)



Homology
more
  • Human Ortholog
    KIFC2, kinesin family member C2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    KIFC2, kinesin family member C2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 90990
    neXtProt AC: NX_Q96AC6
    UniProt: Q96AC6

  • Chr Location
    8q24.3; chr8:144466246-144474116 (+)  GRCh38.p7

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    27 phenotype references
Mice homozygous for a knock-out allele are viable and fertile with no apparent defects in development or behavior.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000004187 Ensembl Gene Model | MGI Sequence Detail 8339 C57BL/6J ±  kb
transcript ENSMUST00000004294 Ensembl | MGI Sequence Detail 3218 Not Applicable  
polypeptide ENSMUSP00000004294 Ensembl | MGI Sequence Detail 792 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • InterPro Domains
    IPR027640 Kinesin-like protein
    IPR001752 Kinesin motor domain
    IPR019821 Kinesin motor domain, conserved site
    IPR036961 Kinesin motor domain superfamily
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 10
    cDNA 8
    Primer pair 1
    Other 1

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-38231
References
more
  • Summaries
    All 54
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 4
    Phenotypes 27
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory