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Acat3
Gene Detail
Symbol

Name
ID
Acat3
acetyl-Coenzyme A acetyltransferase 3
MGI:109182
Synonyms
ACTL
Feature Type
protein coding gene
Genetic Map
Chromosome 17
8.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr17:12923833-12940402 bp, - strand
From VEGA annotation of GRCm38

  16570 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55855  Vertebrate Homology Class
1 human; 2 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: acetyl-CoA acetyltransferase
Gene Tree: Acat3

Human
homologs
Human Homolog ACAT2, acetyl-CoA acetyltransferase 2
NCBI Gene ID 39
neXtProt AC  NX_Q9BWD1
Human Chr (Location)  6q25.3; chr6:159761957-159779055 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human ACAT2
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Interactions
Acat3 interacts with 124 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Component cytoplasm, cytosol, ...
Function acetyl-CoA C-acetyltransferase activity, transferase activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (163)    Tissues (18)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 163
cDNA source data(4)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000028088 (Evidence)
Ensembl Gene ModelENSMUSG00000062480 (Evidence)
Entrez Gene224530 (Evidence)
Consensus CDS ProjectCCDS28398.1
International Mouse Knockout Project StatusAcat3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028088 VEGA Gene Model | MGI Sequence Detail 16570 C57BL/6J ±  kb
transcript OTTMUST00000069581 VEGA | MGI Sequence Detail 2123 Not Applicable 
polypeptide OTTMUSP00000035358 VEGA | MGI Sequence Detail 397 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(4) UniProt(6)
Polymorphisms
SNPs within 2kb(111 from dbSNP Build 137)    SNPs within 2kb including multiple locations(165)
Protein-related
information
ResourceIDDescription
InterPro IPR002155 Thiolase
InterPro IPR020610 Thiolase, active site
InterPro IPR020613 Thiolase, conserved site
InterPro IPR020617 Thiolase, C-terminal
InterPro IPR016039 Thiolase-like
InterPro IPR016038 Thiolase-like, subgroup
InterPro IPR020616 Thiolase, N-terminal
References
(Earliest) J:15561 Ashworth A, Two acetyl-CoA acetyltransferase genes located in the t-complex region of mouse chromosome 17 partially overlap the Tcp-1 and Tcp-1x genes. Genomics. 1993 Nov;18(2):195-8
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(23)
Other
accession IDs
MGD-MRK-38226

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory