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Cpt2 Gene Detail
Summary
  • Symbol
    Cpt2
  • Name
    carnitine palmitoyltransferase 2
  • Synonyms
    CPTII, CPT II
  • Feature Type
    protein coding gene
  • IDs
    MGI:109176
    NCBI Gene: 12896
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr4:107903981-107923610 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      19630 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 50.18 cM
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    CPT2, carnitine palmitoyltransferase 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CPT2, carnitine palmitoyltransferase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CPT1, CPTASE, IIAE4
  • Links
    NCBI Gene ID: 1376
    neXtProt AC: NX_P23786
    UniProt: P23786

  • Chr Location
    1p32.3; chr1:53196429-53214197 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human CPT2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    22 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
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    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000009301 VEGA Gene Model | MGI Sequence Detail 19630 C57BL/6J ±  kb
    transcript OTTMUST00000021110 VEGA | MGI Sequence Detail 2372 Not Applicable  
    polypeptide OTTMUSP00000009669 VEGA | MGI Sequence Detail 658 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      94 from dbSNP Build 142
    • RFLP
    Protein
    Information
    less
    • UniProt
      7 Sequences
    • EC
    • InterPro Domains
      IPR000542 Acyltransferase ChoActase/COT/CPT
    Molecular
    Reagents
    less
    • All nucleic 105
      Genomic 3
      cDNA 99
      Primer pair 3

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-38220, MGI:2140234
    References
    more
    • Summaries
      All 68
      Developmental Gene Expression 10
      Gene Ontology 6
      Phenotypes 22
    • Earliest
      J:16140 Gelb BD, Genomic structure of and a cardiac promoter for the mouse carnitine palmitoyltransferase II gene. Genomics. 1993 Dec;18(3):651-5
    • Latest
      J:261316 Perez-Garcia V, et al., Placentation defects are highly prevalent in embryonic lethal mouse mutants. Nature. 2018 Mar 22;555(7697):463-468

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    05/15/2018
    MGI 6.12
    The Jackson Laboratory