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Dspp
Gene Detail
Symbol

Name
ID
Dspp
dentin sialophosphoprotein
MGI:109172
Synonyms
Dmp3, Dpp, Dsp
Feature Type
protein coding gene
Genetic Map
Chromosome 5
50.59 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:104170712-104180127 bp, + strand
From VEGA annotation of GRCm38

  9416 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Gene Tree: Dspp
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Aging mice homozygous for a reporter/null allele display tooth abnormalities, including enlarged pulp cavities, a widened predentin zone, dentin hypomineralization, pulp exposure, and occasional brittle incisors.
 
Human Diseases Modeled Using Mouse Dspp (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(4)
Interactions
Dspp interacts with 217 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (30 records)
Data Summary: Results (75)    Tissues (35)    Images (35)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 38
RNA in situ 33
Northern blot 2
RT-PCR 2
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) Genomic(5) cDNA(11) Primer pair(1) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000042402 (Evidence)
Ensembl Gene ModelENSMUSG00000053268 (Evidence)
Entrez Gene666279 (Evidence)
UniGene319832
DFCITC1592839
DoTSDT.110655773, DT.110655774, DT.87034810
Consensus CDS ProjectCCDS39190.1
International Mouse Knockout Project StatusDspp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042402 VEGA Gene Model | MGI Sequence Detail 9416 C57BL/6J ±  kb
transcript OTTMUST00000111788 VEGA | MGI Sequence Detail 4431 Not Applicable 
polypeptide OTTMUSP00000062668 VEGA | MGI Sequence Detail 945 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(4)
Polymorphisms
RFLP(2) : SNPs within 2kb(142 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000006712 dentin sialophosphoprotein
References
(Earliest) J:37481 Ritchie HH, et al., Partial cDNA sequencing of mouse dentine sialoprotein and detection of its specific expression by odontoblasts. Arch Oral Biol. 1996 Jun;41(6):571-5
(Latest) J:203117 Li X, et al., A model for the molecular underpinnings of tooth defects in Axenfeld-Rieger syndrome. Hum Mol Genet. 2014 Jan 1;23(1):194-208
All references(63)
Disease annotation references (1)
Other
accession IDs
MGD-MRK-38216

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory