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Ncs1 Gene Detail
Summary
  • Symbol
    Ncs1
  • Name
    neuronal calcium sensor 1
  • Synonyms
    9430075O15Rik, A730032G13Rik, Freq, NCS-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:109166
    NCBI Gene: 14299
  • Gene Overview
    MyGene.info: NCS1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:31245823-31295989 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 21.81 cM, cytoband B
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    334 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109166
protein coding gene Chr2:31245743-31295989 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025583
protein coding gene Chr2:29563623-29613505 (+)
A/J MGP_AJ_G0025561
protein coding gene Chr2:28360855-28412187 (+)
AKR/J MGP_AKRJ_G0025530
protein coding gene Chr2:29325543-29380091 (+)
BALB/cJ MGP_BALBcJ_G0025557
protein coding gene Chr2:28491943-28541826 (+)
C3H/HeJ MGP_C3HHeJ_G0025318
protein coding gene Chr2:29253751-29304084 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026002
protein coding gene Chr2:30518208-30571609 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023410
protein coding gene Chr2:27121842-27172314 (+)
CAST/EiJ MGP_CASTEiJ_G0024780
protein coding gene Chr2:29191332-29241847 (+)
CBA/J MGP_CBAJ_G0025295
protein coding gene Chr2:31605030-31657199 (+)
DBA/2J MGP_DBA2J_G0025428
protein coding gene Chr2:28132775-28184136 (+)
FVB/NJ MGP_FVBNJ_G0025391
protein coding gene Chr2:27980181-28032126 (+)
LP/J MGP_LPJ_G0025514
protein coding gene Chr2:29469015-29519932 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025421
protein coding gene Chr2:31377356-31429671 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026060
protein coding gene Chr2:29245258-29296512 (+)
PWK/PhJ MGP_PWKPhJ_G0024527
protein coding gene Chr2:28022337-28074684 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024327
protein coding gene Chr2:29386698-29442870 (+)
WSB/EiJ MGP_WSBEiJ_G0024848
protein coding gene Chr2:29417049-29469532 (+)



Homology
more
  • Human Ortholog
    NCS1, neuronal calcium sensor 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    NCS1, neuronal calcium sensor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FLUP, FREQ
  • Links
    NCBI Gene ID: 23413
    neXtProt AC: NX_P62166
    UniProt: P62166

  • Chr Location
    9q34.11; chr9:130172578-130237304 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000062661 Ensembl Gene Model | MGI Sequence Detail 50167 C57BL/6J ±  kb
    transcript ENSMUST00000000199 Ensembl | MGI Sequence Detail 4653 Not Applicable  
    polypeptide ENSMUSP00000000199 Ensembl | MGI Sequence Detail 190 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGD-MRK-38210, MGI:1924545, MGI:2139059
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 6
      Gene Ontology 5
      Phenotypes 12
    • Earliest
      J:38125 Olafsson P, et al., The Ca2+ binding protein, frequenin is a nervous system-specific protein in mouse preferentially localized in neurites. Brain Res Mol Brain Res. 1997 Feb;44(1):73-82
    • Latest
      J:246125 Nakamura TY, et al., Possible Signaling Pathways Mediating Neuronal Calcium Sensor-1-Dependent Spatial Learning and Memory in Mice. PLoS One. 2017;12(1):e0170829

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory