Gng8
Gene Detail

Symbol Name ID

Gng8 guanine nucleotide binding protein (G protein), gamma 8 MGI:109163

Synonyms

G(y)8

Feature Type

protein coding gene

Genetic Map

Chromosome 7

9.15 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr7:16891786-16895435 bp, + strand From NCBI annotation of GRCm38   3650 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:7740  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: GTP-binding regulatory protein gamma chain
Gene Tree: Gng8

Human homologs

Human Homolog		GNG8, guanine nucleotide binding protein (G protein), gamma 8
NCBI Gene ID		94235
neXtProt AC		NX_Q9UK08
Human Chr (Location)		19q13.32; chr19:47137333-47137939 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(2) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	G-protein coupled receptor signaling pathway, signal transduction
Component	heterotrimeric G-protein complex, membrane, ...
Function	signal transducer activity

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (6)    Tissues (5)   
Theiler Stages: 4, 28

Assay Type	Results
RT-PCR	6

cDNA source data(8)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(9) cDNA(8) Primer pair(1)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000063594 (Evidence)
Entrez Gene	14709 (Evidence)
UniGene	103770
DFCI	TC1699580
DoTS	DT.483722, DT.55193053, DT.97343201
NIA Mouse Gene Index	U007720
Consensus CDS Project	CCDS20856.1
International Mouse Knockout Project Status	Gng8

Sequences

Length	Strain/Species
genomic	14709	NCBI Gene Model | MGI Sequence Detail	3650	C57BL/6J
transcript	NM_010320	RefSeq | MGI Sequence Detail	920	C57BL/6
polypeptide	P63078	UniProt | EBI | MGI Sequence Detail	70	Not Applicable

All sequences(19) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(28 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR015898	G-protein gamma-like domain
InterPro	IPR001770	G-protein, gamma subunit
Protein Ontology	PR:000008112	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

Graphical View of Protein Domain Structure

References

(Earliest) J:34526 Williams CJ, et al., G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development. Mol Reprod Dev. 1996 Jul;44(3):315-23
(Latest) J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
All references(29)

Other accession IDs

MGD-MRK-38207