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Gng8
Gene Detail
Symbol

Name
ID
Gng8
guanine nucleotide binding protein (G protein), gamma 8
MGI:109163
Synonyms
G(y)8
Feature Type
protein coding gene
Genetic Map
Chromosome 7
9.15 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:16891786-16895435 bp, + strand
From Ensembl annotation of GRCm38

  3650 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7740  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: GTP-binding regulatory protein gamma chain
Gene Tree: Gng8

Human
homologs
Human Homolog GNG8, guanine nucleotide binding protein (G protein), gamma 8
NCBI Gene ID 94235
neXtProt AC  NX_Q9UK08
Human Chr (Location)  19q13.32; chr19:46634076-46634682 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Gng8 interacts with 9 markers (Mir1a-1, Mir1a-2, Mir137, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process G-protein coupled receptor signaling pathway, signal transduction
Component heterotrimeric G-protein complex, membrane, ...
Function signal transducer activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (5)    Tissues (4)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 5
cDNA source data(8)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(8) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000063594 (Evidence)
Entrez Gene14709 (Evidence)
UniGene103770
DFCITC1699580
DoTSDT.55193053, DT.483722, DT.97343201
NIA Mouse Gene IndexU007720
Consensus CDS ProjectCCDS20856.1
International Mouse Knockout Project StatusGng8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000063594 Ensembl Gene Model | MGI Sequence Detail 3650 C57BL/6J ±  kb
transcript ENSMUST00000078182 Ensembl | MGI Sequence Detail 920 Not Applicable 
polypeptide ENSMUSP00000077314 Ensembl | MGI Sequence Detail 70 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(8) UniProt(5)
Polymorphisms
SNPs within 2kb(45 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015898 G-protein gamma-like domain
InterPro IPR001770 G-protein, gamma subunit
Protein Ontology PR:000008112 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
References
(Earliest) J:34526 Williams CJ, et al., G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development. Mol Reprod Dev. 1996 Jul;44(3):315-23
(Latest) J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
All references(30)
Other
accession IDs
MGD-MRK-38207

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory