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Elavl3 Gene Detail
Summary
  • Symbol
    Elavl3
  • Name
    ELAV like RNA binding protein 3
  • Synonyms
    2600009P04Rik, Huc, mHuC
  • Feature Type
    protein coding gene
  • IDs
    MGI:109157
    NCBI Gene: 15571
  • Gene Overview
    MyGene.info: ELAVL3
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:22015005-22052023 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 8.07 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    44 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109157
protein coding gene Chr9:22015005-22052023 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034474
protein coding gene Chr9:19292218-19338943 (-)
A/J MGP_AJ_G0034452
protein coding gene Chr9:18919096-18955059 (-)
AKR/J MGP_AKRJ_G0034378
protein coding gene Chr9:19285293-19321722 (-)
BALB/cJ MGP_BALBcJ_G0034443
protein coding gene Chr9:18801219-18837944 (-)
C3H/HeJ MGP_C3HHeJ_G0034155
protein coding gene Chr9:19589122-19629653 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034964
protein coding gene Chr9:20050161-20110259 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031894
protein coding gene Chr9:18019695-18057100 (-)
CAST/EiJ MGP_CASTEiJ_G0033478
protein coding gene Chr9:19425260-19464974 (-)
CBA/J MGP_CBAJ_G0034128
protein coding gene Chr9:20843360-20885692 (-)
DBA/2J MGP_DBA2J_G0034286
protein coding gene Chr9:18883291-18920408 (-)
FVB/NJ MGP_FVBNJ_G0034229
protein coding gene Chr9:18433086-18470600 (-)
LP/J MGP_LPJ_G0034372
protein coding gene Chr9:19443580-19497017 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034273
protein coding gene Chr9:22398705-22435663 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034984
protein coding gene Chr9:19250836-19290007 (-)
PWK/PhJ MGP_PWKPhJ_G0033183
protein coding gene Chr9:18889670-18927472 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033017
protein coding gene Chr9:19295134-19322591 (-)
WSB/EiJ MGP_WSBEiJ_G0033593
protein coding gene Chr9:18992481-19029544 (-)



Homology
more
  • Human Ortholog
    ELAVL3, ELAV like RNA binding protein 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ELAVL3, ELAV like RNA binding protein 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HUC, HUCL, PLE21
  • Links
    NCBI Gene ID: 1995
    neXtProt AC: NX_Q14576
    UniProt: Q14576

  • Chr Location
    19p13.2; chr19:11451328-11480994 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 3 genetic backgrounds
    2 phenotypes from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit strain-specific preweaning lethality, abnormal cortical hypersynchronization and non-convulsive electropgraphic seizure. Mice heterozygous for the allele exhibit abnormal brain wave pattern and spike wave discharge.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 15571 NCBI Gene Model | MGI Sequence Detail 37019 C57BL/6J ±  kb
transcript NM_010487 RefSeq | MGI Sequence Detail 5027 C57BL/6  
polypeptide Q60900 UniProt | EBI | MGI Sequence Detail 367 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    Genomic 1
    cDNA 17
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-38201, MGI:1913822
References
more
  • Summaries
    All 130
    Developmental Gene Expression 96
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:31495 Abe R, et al., Tissue-specific expression of the gene encoding a mouse RNA binding protein homologous to human HuD antigen. DNA Res. 1994;1(4):175-80
  • Latest
    J:265821 Biehl MJ, et al., Cellular fate decisions in the developing female anteroventral periventricular nucleus are regulated by canonical Notch signaling. Dev Biol. 2018 Oct 1;442(1):87-100

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory