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Ktn1 Gene Detail
Summary
  • Symbol
    Ktn1
  • Name
    kinectin 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:109153
    NCBI Gene: 16709
  • Gene Overview
    MyGene.info: KTN1
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:47648274-47736564 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 24.60 cM, cytoband C2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    584 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109153
 protein coding gene Chr14:47648274-47739894 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021224
 protein coding gene Chr14:41434154-41531075 (+)
A/J MGP_AJ_G0021173
 protein coding gene Chr14:40163202-40257212 (+)
AKR/J MGP_AKRJ_G0021151
 protein coding gene Chr14:41724157-41817316 (+)
BALB/cJ MGP_BALBcJ_G0021175
 protein coding gene Chr14:40221149-40310028 (+)
C3H/HeJ MGP_C3HHeJ_G0020959
 protein coding gene Chr14:41526510-41620707 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021611
 protein coding gene Chr14:43178581-43273500 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019170
 protein coding gene Chr14:39515862-39606629 (+)
CAST/EiJ MGP_CASTEiJ_G0020485
 protein coding gene Chr14:38643427-38741686 (+)
CBA/J MGP_CBAJ_G0020926
 protein coding gene Chr14:44558441-44664967 (+)
DBA/2J MGP_DBA2J_G0021049
 protein coding gene Chr14:40066702-40157084 (+)
FVB/NJ MGP_FVBNJ_G0021034
 protein coding gene Chr14:39798648-39888932 (+)
LP/J MGP_LPJ_G0021118
 protein coding gene Chr14:41682339-41776180 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021059
 protein coding gene Chr14:43908789-44003548 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021644
 protein coding gene Chr14:41259974-41358241 (+)
PWK/PhJ MGP_PWKPhJ_G0020233
 protein coding gene Chr14:36937989-37027843 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020058
 protein coding gene Chr14:37397590-37495732 (+)
WSB/EiJ MGP_WSBEiJ_G0020541
 protein coding gene Chr14:41373838-41466521 (+)



Homology
more
  • Human Ortholog
    KTN1, kinectin 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    KTN1, kinectin 1
    Orthology source: HGNC
  • Synonyms
    CG1, KNT, MU-RMS-40.19
  • Links
    NCBI Gene ID: 3895
    neXtProt AC: NX_Q86UP2
    UniProt: Q86UP2

  • Chr Location
    14q22.3; chr14:55580207-55684584 (+)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 7397
    1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: KTN1
  • Gene Tree
    Ktn1
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    8 phenotype references
Mice homozygous for a targeted null mutation or a floxed allele exhibit no discernable phenotype; mice are viable and fertile up to one year of age.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    18
  • Tissues
    15
  • cDNA Data
    235
  • Literature Summary
    4
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 16709 NCBI Gene Model | MGI Sequence Detail 88291 C57BL/6J ±  kb
transcript NM_008477 RefSeq | MGI Sequence Detail 4511 C57BL/6  
polypeptide Q61595 UniProt | EBI | MGI Sequence Detail 1327 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 237
    cDNA 235
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-38197
References
more
  • Summaries
    All 33
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:36633 Leung E, et al., Cloning of novel kinectin splice variants with alternative C-termini: structure, distribution and evolution of mouse kinectin. Immunol Cell Biol. 1996 Oct;74(5):421-33
  • Latest
    J:256244 Valnegri P, et al., RNF8/UBC13 ubiquitin signaling suppresses synapse formation in the mammalian brain. Nat Commun. 2017 Nov 2;8(1):1271
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/18/2020
MGI 6.14 		The Jackson Laboratory