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Ktn1 Gene Detail
Summary
  • Symbol
    Ktn1
  • Name
    kinectin 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:109153
    NCBI Gene: 16709
  • Gene Overview
    MyGene.info: KTN1
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    Chr14:47648448-47736564 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      88117 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 24.60 cM, cytoband C2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    KTN1, kinectin 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    KTN1, kinectin 1
    Orthology source: HGNC
  • Synonyms
    CG1, KNT, MU-RMS-40.19
  • Links
    NCBI Gene ID: 3895
    neXtProt AC: NX_Q86UP2
    UniProt: Q86UP2

  • Chr Location
    14q22.3; chr14:55580207-55684584 (+)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 7397
    1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: KTN1
  • Gene Tree
    Ktn1
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    8 phenotype references
Mice homozygous for a targeted null mutation or a floxed allele exhibit no discernable phenotype; mice are viable and fertile up to one year of age.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    18
  • Tissues
    15
  • cDNA Data
    234
  • Literature Summary
    4
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000045014 VEGA Gene Model | MGI Sequence Detail 88117 C57BL/6J ±  kb
transcript OTTMUST00000118304 VEGA | MGI Sequence Detail 4608 Not Applicable  
polypeptide OTTMUSP00000066041 VEGA | MGI Sequence Detail 1327 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    581 from dbSNP Build 142
Protein
Information
less
  • UniProt
    20 Sequences
  • InterPro Domains
    IPR024854 Kinectin
    IPR007794 Ribosome receptor lysine/proline rich
Molecular
Reagents
less
  • All nucleic 236
    cDNA 234
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-38197
References
more
  • Summaries
    All 31
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:36633 Leung E, et al., Cloning of novel kinectin splice variants with alternative C-termini: structure, distribution and evolution of mouse kinectin. Immunol Cell Biol. 1996 Oct;74(5):421-33
  • Latest
    J:228946 Wei N, et al., SRSF10 Plays a Role in Myoblast Differentiation and Glucose Production via Regulation of Alternative Splicing. Cell Rep. 2015 Nov 24;13(8):1647-57
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/15/2018
MGI 6.12 		The Jackson Laboratory