About   Help   FAQ
Snap91 Gene Detail
Summary
  • Symbol
    Snap91
  • Name
    synaptosomal-associated protein 91
  • Synonyms
    91kDa, AP180, F1-20, mKIAA0656
  • Feature Type
    protein coding gene
  • IDs
    MGI:109132
    NCBI Gene: 20616
  • Gene Overview
    MyGene.info: SNAP91
Location & Maps
more
  • Sequence Map
    Chr9:86765923-86880654 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      114732 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 46.58 cM, cytoband E3.2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SNAP91, synaptosome associated protein 91
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SNAP91, synaptosome associated protein 91
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AP180, CALM
  • Links
    NCBI Gene ID: 9892
    neXtProt AC: NX_O60641

  • Chr Location
    6q14.2; chr6:83552885-83709408 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 8429
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: SNAP91
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Snap91
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000045050 VEGA Gene Model | MGI Sequence Detail 114732 C57BL/6J ±  kb
transcript OTTMUST00000118387 VEGA | MGI Sequence Detail 4150 Not Applicable  
polypeptide OTTMUSP00000066085 VEGA | MGI Sequence Detail 838 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    894 from dbSNP Build 142
Protein
Information
less
  • UniProt
    10 Sequences
  • Protein Ontology
    PR:000015315 clathrin coat assembly protein AP180
  • InterPro Domains
    IPR011417 AP180 N-terminal homology (ANTH) domain
    IPR030428 Clathrin coat assembly protein AP180, vertebrate
    IPR013809 ENTH domain
    IPR008942 ENTH/VHS
    IPR014712 Phosphoinositide-binding clathrin adaptor, domain 2
Molecular
Reagents
less
  • All nucleic 34
    cDNA 30
    Primer pair 4

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-38176
References
more
  • Summaries
    All 39
    Developmental Gene Expression 9
    Gene Ontology 8
    Phenotypes 4
  • Earliest
    J:1152 Zhou S, et al., Characterization of a novel synapse-specific protein. II. cDNA cloning and sequence analysis of the F1-20 protein. J Neurosci. 1992 Jun;12(6):2144-55
  • Latest
    J:228428 Koo SJ, et al., Vesicular Synaptobrevin/VAMP2 Levels Guarded by AP180 Control Efficient Neurotransmission. Neuron. 2015 Oct 21;88(2):330-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/27/2016
MGI 6.05
The Jackson Laboratory