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Taf6 Gene Detail
Summary
  • Symbol
    Taf6
  • Name
    TATA-box binding protein associated factor 6
  • Synonyms
    80kDa, p80, Taf2e
  • Feature Type
    protein coding gene
  • IDs
    MGI:109129
    NCBI Gene: 21343
  • Gene Overview
    MyGene.info: TAF6
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:138178617-138187446 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 76.98 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    67 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109129
protein coding gene Chr5:138178617-138187451 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030259
protein coding gene Chr5:142974579-142983387 (-)
A/J MGP_AJ_G0030227
protein coding gene Chr5:136792995-136801814 (-)
AKR/J MGP_AKRJ_G0030159
protein coding gene Chr5:141245644-141254465 (-)
BALB/cJ MGP_BALBcJ_G0030241
protein coding gene Chr5:138152607-138161421 (-)
C3H/HeJ MGP_C3HHeJ_G0029954
protein coding gene Chr5:141873086-141881899 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030688
protein coding gene Chr5:148327975-148336808 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027906
protein coding gene Chr5:130927097-130936026 (-)
CAST/EiJ MGP_CASTEiJ_G0029360
protein coding gene Chr5:141254698-141263519 (-)
CBA/J MGP_CBAJ_G0029925
protein coding gene Chr5:154204891-154213712 (-)
DBA/2J MGP_DBA2J_G0030073
protein coding gene Chr5:136692453-136701271 (-)
FVB/NJ MGP_FVBNJ_G0030031
protein coding gene Chr5:135856864-135865687 (-)
LP/J MGP_LPJ_G0030162
protein coding gene Chr5:143514560-143523384 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030062
protein coding gene Chr5:157030297-157039116 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030729
protein coding gene Chr5:141081192-141090011 (-)
PWK/PhJ MGP_PWKPhJ_G0029074
protein coding gene Chr5:135751227-135759819 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028910
protein coding gene Chr5:138641925-138650626 (-)
WSB/EiJ MGP_WSBEiJ_G0029435
protein coding gene Chr5:141770618-141779464 (-)



Homology
more
  • Human Ortholog
    TAF6, TATA-box binding protein associated factor 6
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TAF6, TATA-box binding protein associated factor 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ALYUS, MGC:8964, TAF2E, TAFII70, TAF(II)70, TAFII-70, TAFII80, TAF(II)80, TAFII-80, TAFII85
  • Links
    NCBI Gene ID: 6878
    neXtProt AC: NX_P49848
    UniProt: P49848

  • Chr Location
    7q22.1; chr7:100107070-100119858 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a transgenic gene disruption may exhibit preimplantation lethality.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 21343 NCBI Gene Model | MGI Sequence Detail 8830 C57BL/6J ±  kb
transcript NM_001356600 RefSeq | MGI Sequence Detail 2411 C57BL/6  
polypeptide Q62311 UniProt | EBI | MGI Sequence Detail 678 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 53
    cDNA 52
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-38173, MGI:2141226
References
more
  • Summaries
    All 51
    Developmental Gene Expression 11
    Gene Ontology 9
    Phenotypes 12
  • Earliest
    J:28371 Umehara T, et al., Isolation of a cDNA encoding a mouse TFIID subunit containing histone H4 homology. Gene. 1995 Aug 19;161(2):301-2
  • Latest
    J:245730 Bardot P, et al., The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo. Development. 2017 Oct 15;144(20):3808-3818

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory