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Meis3 Gene Detail
Summary
  • Symbol
    Meis3
  • Name
    Meis homeobox 3
  • Synonyms
    Mrg2
  • Feature Type
    protein coding gene
  • IDs
    MGI:108519
    NCBI Gene: 17537
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:16175096-16186510 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 8.76 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    110 from dbSNP Build 142
  • Strain Annotations
    17
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108519
protein coding gene Chr7:16175090-16186510 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031701
protein coding gene Chr7:13832274-13847363 (+)
A/J MGP_AJ_G0031673
protein coding gene Chr7:13636963-13648964 (+)
AKR/J MGP_AKRJ_G0031598
protein coding gene Chr7:13938570-13949885 (+)
BALB/cJ MGP_BALBcJ_G0031680
protein coding gene Chr7:13734894-13746116 (+)
C3H/HeJ MGP_C3HHeJ_G0031402
protein coding gene Chr7:14114856-14126731 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032146
protein coding gene Chr7:14589403-14602471 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029225
protein coding gene Chr7:15191806-15202951 (+)
CAST/EiJ MGP_CASTEiJ_G0030753
protein coding gene Chr7:10886327-10897645 (+)
CBA/J MGP_CBAJ_G0031361
protein coding gene Chr7:15043259-15060283 (+)
DBA/2J MGP_DBA2J_G0031517
protein coding gene Chr7:13521018-13532242 (+)
FVB/NJ MGP_FVBNJ_G0031473
protein coding gene Chr7:13414154-13426265 (+)
LP/J MGP_LPJ_G0031602
protein coding gene Chr7:14107113-14119839 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031508
protein coding gene Chr7:15015289-15029753 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032175
protein coding gene Chr7:13715495-13727427 (+)
PWK/PhJ MGP_PWKPhJ_G0030477
protein coding gene Chr7:11028781-11041870 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0030850
protein coding gene Chr7:13751366-13765730 (+)



Homology
more
  • Human Ortholog
    MEIS3, Meis homeobox 3
  • Vertebrate Orthologs
    6
  • Human Ortholog
    MEIS3, Meis homeobox 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MRG2
  • Links
    NCBI Gene ID: 56917
    neXtProt AC: NX_Q99687
    UniProt: Q99687

  • Chr Location
    19q13.32; chr19:47403118-47422315 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 17537 NCBI Gene Model | MGI Sequence Detail 11415 C57BL/6J ±  kb
transcript NM_001302472 RefSeq | MGI Sequence Detail 1791 C57BL/6  
polypeptide P97368 UniProt | EBI | MGI Sequence Detail 378 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    Genomic 3
    cDNA 16

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-37563, MGI:2141999
References
more
  • Summaries
    All 51
    Developmental Gene Expression 18
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:37072 Nakamura T, et al., Identification of a new family of Pbx-related homeobox genes. Oncogene. 1996 Nov 21;13(10):2235-42
  • Latest
    J:230425 Bouilloux F, et al., Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory