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Meis3 Gene Detail
Summary
  • Symbol
    Meis3
  • Name
    Meis homeobox 3
  • Synonyms
    Mrg2
  • Feature Type
    protein coding gene
  • IDs
    MGI:108519
    NCBI Gene: 17537
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:15909015-15920429 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 8.76 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    100 from dbSNP Build 142
  • Strain Annotations
    17
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108519
protein coding gene Chr7:15908684-15920435 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031701
protein coding gene Chr7:13832274-13847363 (+)
A/J MGP_AJ_G0031673
protein coding gene Chr7:13636963-13648964 (+)
AKR/J MGP_AKRJ_G0031598
protein coding gene Chr7:13938570-13949885 (+)
BALB/cJ MGP_BALBcJ_G0031680
protein coding gene Chr7:13734894-13746116 (+)
C3H/HeJ MGP_C3HHeJ_G0031402
protein coding gene Chr7:14114856-14126731 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032146
protein coding gene Chr7:14589403-14602471 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029225
protein coding gene Chr7:15191806-15202951 (+)
CAST/EiJ MGP_CASTEiJ_G0030753
protein coding gene Chr7:10886327-10897645 (+)
CBA/J MGP_CBAJ_G0031361
protein coding gene Chr7:15043259-15060283 (+)
DBA/2J MGP_DBA2J_G0031517
protein coding gene Chr7:13521018-13532242 (+)
FVB/NJ MGP_FVBNJ_G0031473
protein coding gene Chr7:13414154-13426265 (+)
LP/J MGP_LPJ_G0031602
protein coding gene Chr7:14107113-14119839 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031508
protein coding gene Chr7:15015289-15029753 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032175
protein coding gene Chr7:13715495-13727427 (+)
PWK/PhJ MGP_PWKPhJ_G0030477
protein coding gene Chr7:11028781-11041870 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0030850
protein coding gene Chr7:13751366-13765730 (+)



Homology
more
  • Human Ortholog
    MEIS3, Meis homeobox 3
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MEIS3, Meis homeobox 3
  • Synonyms
    MRG2
  • Links
    NCBI Gene ID: 56917
    neXtProt AC: NX_Q99687
    UniProt: Q99687

  • Chr Location
    19q13.32; chr19:47403118-47422315 (-)  GRCh38.p7

  • Human Ortholog
    MEIS3P1, Meis homeobox 3 pseudogene 1
  • Synonyms
    MEIS3, MEIS4, MRG2
  • Links
    NCBI Gene ID: 4213
    UniProt: A6NDR6

  • Chr Location
    17p12; chr17:15786850-15789705 (+)  GRCh38.p7

  • Human Ortholog
    MEIS3P2, Meis homeobox 3 pseudogene 2
  • Links
    NCBI Gene ID: 257468

  • Chr Location
    17p11.2; chr17:20588849-20590815 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    18 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000041420 Ensembl Gene Model | MGI Sequence Detail 11415 C57BL/6J ±  kb
    transcript ENSMUST00000002495 Ensembl | MGI Sequence Detail 1731 Not Applicable  
    polypeptide ENSMUSP00000002495 Ensembl | MGI Sequence Detail 378 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 20
      Genomic 3
      cDNA 16
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-37563, MGI:2141999
    References
    more
    • Summaries
      All 60
      Developmental Gene Expression 22
      Gene Ontology 6
      Phenotypes 9
    • Earliest
      J:37072 Nakamura T, et al., Identification of a new family of Pbx-related homeobox genes. Oncogene. 1996 Nov 21;13(10):2235-42
    • Latest
      J:296650 England AR, et al., Identification and characterization of cellular heterogeneity within the developing renal interstitium. Development. 2020 Aug 14;147(15):dev190108

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    08/03/2022
    MGI 6.21
    The Jackson Laboratory