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St5 Gene Detail
Summary
  • Symbol
    St5
  • Name
    suppression of tumorigenicity 5
  • Synonyms
    2010004M01Rik, 2610305K15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:108517
    NCBI Gene: 76954
  • Gene Overview
    MyGene.info: ST5
Location & Maps
more
  • Sequence Map
    Chr7:109523920-109703605 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      179686 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 57.27 cM, cytoband F2
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    ST5, suppression of tumorigenicity 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ST5, suppression of tumorigenicity 5
    Orthology source: HomoloGene
  • Synonyms
    DENND2B, HTS1, p126
  • Links
    NCBI Gene ID: 6764
    neXtProt AC: NX_P78524

  • Chr Location
    11p15; chr11:8693352-8910951 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 3951
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: ST5
  • Gene Tree
    St5
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
  • All Mutations and Alleles
    170
  • Chemically induced (other)
    1
  • Gene trapped
    168
  • Radiation induced
    1
  • Genomic Mutations
    2 involving St5
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000060125 VEGA Gene Model | MGI Sequence Detail 179686 C57BL/6J ±  kb
transcript OTTMUST00000147169 VEGA | MGI Sequence Detail 4612 Not Applicable  
polypeptide OTTMUSP00000076598 VEGA | MGI Sequence Detail 1134 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1142 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    Genomic 6
    cDNA 11
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-37561, MGI:1919751, MGI:1924204
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 14
  • Earliest
    J:32718 Kleyn PW, et al., Identification and characterization of the mouse obesity gene tubby: a member of a novel gene family. Cell. 1996 Apr 19;85(2):281-90
  • Latest
    J:157306 Gohring I, et al., Disruption of ST5 is associated with mental retardation and multiple congenital anomalies. J Med Genet. 2010 Feb;47(2):91-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory