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St5
Gene Detail
Symbol

Name
ID
St5
suppression of tumorigenicity 5
MGI:108517
Synonyms
2010004M01Rik, 2610305K15Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 7
57.27 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr7:109523911-109617147 bp, - strand
From Ensembl annotation of GRCm38

  93237 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3951  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ST5
Gene Tree: St5

Human
homologs
ST5, suppression of tumorigenicity 5
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 6764
neXtProt AC: NX_P78524

Human Synonyms: DENND2B, HTS1, p126

Human Chr (Location): 11p15; chr11:8693352-8910951 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(167) : Gene trapped(167)
Incidental mutations (data from Mutagenetix , APF )
Interactions
St5 interacts with 234 markers (Mir7-1, Mir10b, Mir15a, ...)
Expression
Literature Summary: (1 records)
Data Summary: Results (44)    Tissues (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 44
cDNA source data(11)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase st5 ; ZFIN st5    NEW 
Molecular
reagents
All nucleic(19) Genomic(6) cDNA(11) Primer pair(2)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000031024 (Evidence)
Entrez Gene 76954 (Evidence)
DFCI TC1603460, TC1577706, TC1603566
DoTS DT.101407493, DT.101299003, DT.101714725, DT.489943, DT.55231879
NIA Mouse Gene Index U029106
Consensus CDS Project CCDS21734.1, CCDS21735.1
International Mouse Phenotyping Consortium Status St5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031024 Ensembl Gene Model | MGI Sequence Detail 93237 C57BL/6J ±  kb
transcript ENSMUST00000079282 Ensembl | MGI Sequence Detail 4255 Not Applicable 
polypeptide ENSMUSP00000078264 Ensembl | MGI Sequence Detail 1134 Not Applicable 

For the selected sequences
All sequences(60) RefSeq(24) UniProt(3)
Polymorphisms
SNPs within 2kb(761 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005112 dDENN domain
InterPro IPR001194 DENN domain
InterPro IPR005113 uDENN domain
Protein Ontology PR:000015684 suppression of tumorigenicity 5 protein
References
(Earliest) J:32718 Kleyn PW, et al., Identification and characterization of the mouse obesity gene tubby: a member of a novel gene family. Cell. 1996 Apr 19;85(2):281-90
(Latest) J:157306 Gohring I, et al., Disruption of ST5 is associated with mental retardation and multiple congenital anomalies. J Med Genet. 2010 Feb;47(2):91-8
All references(32)
Other
accession IDs
MGD-MRK-37561, MGI:1919751, MGI:1924204

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory