Adcy9
Gene Detail

Symbol Name ID

Adcy9 adenylate cyclase 9 MGI:108450

Synonyms

ACtp10, D16Wsu65e, mKIAA0520

Feature Type

protein coding gene

Genetic Map

Chromosome 16

2.42 cM, cytoband B1
Detailed Genetic Map ± 1 cM


Mapping data(6)

Sequence Map

Chr16:4287529-4420498 bp, - strand From VEGA annotation of GRCm38   132970 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Adcy9 ± 2 cM)

Gene Tree: Adcy9

Human ortholog

ADCY9 adenylate cyclase 9 NCBI Gene ID 115
Human Synonyms: AC9
Human Chr16:4012652-4166186 bp, - strand Reference GRCh37.p2 Primary Assembly

Alleles and phenotypes

All alleles(4) : Targeted(2) Gene trapped(2)
 

Mice homozygous for disruptions in this gene show an increased IgG1 response to ovalbumin challenge.

 

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	activation of adenylate cyclase activity, cAMP biosynthetic process, ...
Component	integral to membrane, membrane, ...
Function	adenylate cyclase activity, ATP binding, ...

External Resources: FuncBase

Expression

Literature Summary: (8 records)
Data Summary: Results (163)    Tissues (127)    Images (19)
Theiler Stages: 11, 22, 23, 28

Assay Type	Results
RNA in situ	157
RT-PCR	6

cDNA source data(23)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(27) cDNA(24) Primer pair(2) Other(1)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000027177 (Evidence)
Ensembl Gene Model	ENSMUSG00000005580 (Evidence)
Entrez Gene	11515 (Evidence)
DFCI	TC1581343, TC1736968
DoTS	DT.110716002, DT.55108410
NIA Mouse Gene Index	U036736, U176354
EC	4.6.1.1
Consensus CDS Project	CCDS27917.1
International Mouse Knockout Project Status	Adcy9

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027177	VEGA Gene Model | MGI Sequence Detail	132970	C57BL/6J
transcript	OTTMUST00000067216	VEGA | MGI Sequence Detail	4507	Not Applicable
polypeptide	OTTMUSP00000033787	VEGA | MGI Sequence Detail	1353	Not Applicable

All sequences(35) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(508 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase
InterPro	IPR018297	Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site
Protein Ontology	PR:000003760	adenylate cyclase type 9

References

(Earliest) J:28928 Paterson JM, et al., Control of a novel adenylyl cyclase by calcineurin. Biochem Biophys Res Commun. 1995 Sep 25;214(3):1000-8
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(43)

Other accession IDs

MGD-MRK-33986, MGD-MRK-37494, MGI:106294, MGI:2146626