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Adcy9 Gene Detail
Summary
  • Symbol
    Adcy9
  • Name
    adenylate cyclase 9
  • Synonyms
    ACtp10, D16Wsu65e, mKIAA0520
  • Feature Type
    protein coding gene
  • IDs
    MGI:108450
    NCBI Gene: 11515
  • Gene Overview
    MyGene.info: ADCY9
Location & Maps
more
  • Sequence Map
    Chr16:4287529-4420498 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      132970 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 2.42 cM, cytoband B1
  • Mapping Data
    6 experiments
Homology
more
  • Human Ortholog
    ADCY9, adenylate cyclase 9
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ADCY9, adenylate cyclase 9
    Orthology source: HomoloGene
  • Synonyms
    AC9, ACIX
  • Links
    NCBI Gene ID: 115
    neXtProt AC: NX_O60503

  • Chr Location
    16p13.3; chr16:3953387-4116185 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene show an increased IgG1 response to ovalbumin challenge.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027177 VEGA Gene Model | MGI Sequence Detail 132970 C57BL/6J ±  kb
transcript OTTMUST00000067216 VEGA | MGI Sequence Detail 4507 Not Applicable  
polypeptide OTTMUSP00000033787 VEGA | MGI Sequence Detail 1353 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    769 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000003760 adenylate cyclase type 9
  • EC
  • InterPro Domains
    IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase
    IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved site
    IPR029787 Nucleotide cyclase
Molecular
Reagents
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  • All nucleic 27
    cDNA 24
    Primer pair 2
    Other 1

    Microarray probesets 6
Other
Accession IDs
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MGD-MRK-33986, MGD-MRK-37494, MGI:106294, MGI:2146626
References
more
  • Summaries
    All 44
    Developmental Gene Expression 8
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:28928 Paterson JM, et al., Control of a novel adenylyl cyclase by calcineurin. Biochem Biophys Res Commun. 1995 Sep 25;214(3):1000-8
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory