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Adcy9 Gene Detail
Summary
  • Symbol
    Adcy9
  • Name
    adenylate cyclase 9
  • Synonyms
    ACtp10, D16Wsu65e, mKIAA0520
  • Feature Type
    protein coding gene
  • IDs
    MGI:108450
    NCBI Gene: 11515
  • Gene Overview
    MyGene.info: ADCY9
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:4287529-4420498 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 2.42 cM, cytoband B1
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    769 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108450
protein coding gene Chr16:4284886-4437236 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022462
protein coding gene Chr16:757779-888724 (-)
A/J MGP_AJ_G0022424
protein coding gene Chr16:616885-743657 (-)
AKR/J MGP_AKRJ_G0022401
protein coding gene Chr16:767471-898013 (-)
BALB/cJ MGP_BALBcJ_G0022429
protein coding gene Chr16:758981-887483 (-)
C3H/HeJ MGP_C3HHeJ_G0022196
protein coding gene Chr16:805326-936248 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022878
protein coding gene Chr16:816967-956604 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020399
protein coding gene Chr16:560973-686536 (-)
CAST/EiJ MGP_CASTEiJ_G0021722
protein coding gene Chr16:777760-920113 (-)
CBA/J MGP_CBAJ_G0022165
protein coding gene Chr16:894789-1041449 (-)
DBA/2J MGP_DBA2J_G0022296
protein coding gene Chr16:720822-853746 (-)
FVB/NJ MGP_FVBNJ_G0022271
protein coding gene Chr16:694321-829711 (-)
LP/J MGP_LPJ_G0022364
protein coding gene Chr16:762372-901600 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022293
protein coding gene Chr16:765041-904516 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022890
protein coding gene Chr16:743181-882010 (-)
PWK/PhJ MGP_PWKPhJ_G0021462
protein coding gene Chr16:774467-906733 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021293
protein coding gene Chr16:839701-972718 (-)
WSB/EiJ MGP_WSBEiJ_G0021771
protein coding gene Chr16:764455-900552 (-)



Homology
more
  • Human Ortholog
    ADCY9, adenylate cyclase 9
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ADCY9, adenylate cyclase 9
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AC9, ACIX
  • Links
    NCBI Gene ID: 115
    neXtProt AC: NX_O60503
    UniProt: O60503

  • Chr Location
    16p13.3; chr16:3953387-4116185 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    24 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene show an increased IgG1 response to ovalbumin challenge.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000005580 Ensembl Gene Model | MGI Sequence Detail 132970 C57BL/6J ±  kb
    transcript ENSMUST00000117801 Ensembl | MGI Sequence Detail 4507 Not Applicable  
    polypeptide ENSMUSP00000113498 Ensembl | MGI Sequence Detail 1353 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 28
      cDNA 25
      Primer pair 2
      Other 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGD-MRK-33986, MGD-MRK-37494, MGI:106294, MGI:2146626
    References
    more
    • Summaries
      All 53
      Developmental Gene Expression 10
      Gene Ontology 8
      Phenotypes 13
    • Earliest
      J:28928 Paterson JM, et al., Control of a novel adenylyl cyclase by calcineurin. Biochem Biophys Res Commun. 1995 Sep 25;214(3):1000-8
    • Latest
      J:261316 Perez-Garcia V, et al., Placentation defects are highly prevalent in embryonic lethal mouse mutants. Nature. 2018 Mar 22;555(7697):463-468

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory