Camp
Gene Detail

Symbol Name ID

Camp cathelicidin antimicrobial peptide MGI:108443

Synonyms

CAP18, Cnlp, Cramp, FALL39, MCLP

Feature Type

protein coding gene

Genetic Map

Chromosome 9

59.80 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr9:109847375-109849456 bp, - strand From VEGA annotation of GRCm38   2082 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:110678  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 9 cattle; 1 dog

Gene Tree: Camp

Human homologs

Human Homolog		CAMP, cathelicidin antimicrobial peptide
NCBI Gene ID		820
neXtProt AC		NX_P49913
Human Synonyms		CAP18, CAP-18, CRAMP, FALL39, FALL-39, LL37
Human Chr (Location)		3p21.3; chr3:48264837-48266981 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(20) : Targeted(3) Gene trapped(17)
 

Mice homozygous for a knock-out allele are more susceptible to necrotic skin infection caused by Group A Streptococcus and urinary tract infection caused by uropathogenic E. coli.

 

Gene Ontology (GO) classifications

All GO classifications: (21 annotations)

Process	defense response, defense response to bacterium, ...
Component	cell projection, cytoplasm, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (24)    Tissues (22)    Images (4)
Theiler Stages: 20, 21, 22, 23, 24, 26, 28

Assay Type	Results
Immunohistochemistry	5
Northern blot	7
RT-PCR	12

cDNA source data(15)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(19) cDNA(16) Primer pair(2) Other(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000020575 (Evidence)
Ensembl Gene Model	ENSMUSG00000038357 (Evidence)
Entrez Gene	12796 (Evidence)
UniGene	3834
DFCI	TC1580444
DoTS	DT.530614
NIA Mouse Gene Index	U031357
Consensus CDS Project	CCDS52934.1
International Mouse Knockout Project Status	Camp

Sequences

Length	Strain/Species
genomic	OTTMUSG00000020575	VEGA Gene Model | MGI Sequence Detail	2082	C57BL/6J
transcript	OTTMUST00000048760	VEGA | MGI Sequence Detail	601	Not Applicable
polypeptide	OTTMUSP00000022449	VEGA | MGI Sequence Detail	172	Not Applicable

All sequences(20) RefSeq(2) UniProt(2)

Polymorphisms

RFLP(1) : SNPs(27 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001894	Cathelicidin
InterPro	IPR022746	Cathelicidin, antimicrobial peptide, C-terminal
InterPro	IPR018216	Cathelicidin, conserved site
Protein Ontology	PR:000025851	cathelicidin antimicrobial peptide

References

(Earliest) J:34599 Popsueva AE, et al., A novel murine cathelin-like protein expressed in bone marrow. FEBS Lett. 1996 Aug 5;391(1-2):5-8
(Latest) J:194792 Strandberg KL, et al., An altered immune response, but not individual cationic antimicrobial peptides, is associated with the oral attenuation of Ara4N-deficient Salmonella enterica serovar Typhimurium in mice. PLoS One. 2012;7(11):e49588
All references(63)

Other accession IDs

MGD-MRK-37487, MGI:892985