About   Help   FAQ
Camp
Gene Detail
Symbol

Name
ID
Camp
cathelicidin antimicrobial peptide
MGI:108443
Synonyms
CAP18, Cnlp, Cramp, FALL39, MCLP
Feature Type
protein coding gene
Genetic Map
Chromosome 9
59.80 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:109847379-109849617 bp, - strand
From VEGA annotation of GRCm38

  2239 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:110678  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 9 cattle; 1 dog

HCOP human homology predictions: CAMP
Gene Tree: Camp

Human
homologs
CAMP, cathelicidin antimicrobial peptide
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 820
neXtProt AC: NX_P49913

Human Synonyms: CAP18, CAP-18, CRAMP, FALL39, FALL-39, HSD26, LL37

Human Chr (Location): 3p21.3; chr3:48223347-48225491 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Gene trapped(17) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele are more susceptible to necrotic skin infection caused by Group A Streptococcus and urinary tract infection caused by uropathogenic E. coli and F. solani-induced keratitis.
 
Interactions
Camp interacts with 4 markers (Mir208b, Mir875, Mir1224, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process antibacterial humoral response, defense response, ...
Component cell projection, cytoplasm, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (22)    Tissues (19)    Images (4)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 3
Northern blot 7
RT-PCR 12
cDNA source data(15)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) cDNA(16) Primer pair(2) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000020575 (Evidence)
Ensembl Gene Model ENSMUSG00000038357 (Evidence)
Entrez Gene 12796 (Evidence)
UniGene 3834
DFCI TC1580444
DoTS DT.530614
NIA Mouse Gene Index U031357
Consensus CDS Project CCDS52934.1
International Mouse Phenotyping Consortium Status Camp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020575 VEGA Gene Model | MGI Sequence Detail 2239 C57BL/6J ±  kb
transcript OTTMUST00000048760 VEGA | MGI Sequence Detail 758 Not Applicable 
polypeptide OTTMUSP00000022449 VEGA | MGI Sequence Detail 172 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(2)
Polymorphisms
RFLP(1) : SNPs within 2kb(44 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001894 Cathelicidin
InterPro IPR022746 Cathelicidin, antimicrobial peptide, C-terminal
InterPro IPR018216 Cathelicidin, conserved site
Protein Ontology PR:000025851 cathelicidin antimicrobial peptide
References
(Earliest) J:34599 Popsueva AE, et al., A novel murine cathelin-like protein expressed in bone marrow. FEBS Lett. 1996 Aug 5;391(1-2):5-8
(Latest) J:212860 Wantha S, et al., Neutrophil-derived cathelicidin promotes adhesion of classical monocytes. Circ Res. 2013 Mar 1;112(5):792-801
All references(69)
Other
accession IDs
MGD-MRK-37487, MGI:892985

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/25/2015
MGI 6.0
The Jackson Laboratory