Camp MGI Mouse Gene Detail - MGI:108443 - cathelicidin antimicrobial peptide

Symbol

Camp
Name

cathelicidin antimicrobial peptide
Synonyms

CAP18, Cnlp, Cramp, FALL39, MCLP

Feature Type

protein coding gene
IDs

MGI:108443
NCBI Gene: 12796
Alliance

genome feature page
Transcription Start Sites

2 TSS

Sequence Map

Chr9:109676445-109678524 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 9, 59.80 cM
Mapping Data

2 experiments

SNPs within 2kb

185 from dbSNP Build 142
Strain Annotations

19
RFLP

1

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_108443	protein coding gene	Chr9:109676445-109678685 (-)
129S1/SvImJ	ENSMUSG00200038497	protein coding gene	Chr9:106769079-106771334 (-)
A/J	ENSMUSG00195043947	protein coding gene	Chr9:106062175-106064412 (-)
AKR/J	ENSMUSG00220026414	protein coding gene	Chr9:106397904-106400141 (-)
BALB/cJ	ENSMUSG00180027757	protein coding gene	Chr9:106517100-106519336 (-)
C3H/HeJ	ENSMUSG00175033876	protein coding gene	Chr9:106732999-106735236 (-)
C57BL/6NJ	ENSMUSG00215015214	protein coding gene	Chr9:106613143-106615382 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0032722	protein coding gene	Chr9:105131352-105133408 (-)
CAST/EiJ	ENSTCUG00005028348	protein coding gene	Chr9:106432007-106434231 (-)
CBA/J	ENSMUSG00210030759	protein coding gene	Chr9:106445006-106447210 (-)
DBA/2J	ENSMUSG00185041408	protein coding gene	Chr9:106780988-106783226 (-)
FVB/NJ	ENSMUSG00205049289	protein coding gene	Chr9:106710623-106712877 (-)
JF1/MsJ	ENSUMUG00000028865	protein coding gene	Chr9:106547329-106549533 (-)
LP/J	ENSMUSG00230043895	protein coding gene	Chr9:106901296-106903550 (-)
NOD/ShiLtJ	ENSMUSG00190044494	protein coding gene	Chr9:106368633-106370870 (-)
NZO/HlLtJ	ENSMUSG00225024235	protein coding gene	Chr9:107150775-107153003 (-)
PWK/PhJ	ENSLUMG00010036307	protein coding gene	Chr9:106562938-106565156 (-)
SPRET/EiJ	ENSMSPG00010043033	protein coding gene	Chr9:108355043-108357269 (-)
WSB/EiJ	ENSIUOG00005045766	protein coding gene	Chr9:105826369-105828597 (-)

Human Ortholog

CAMP, cathelicidin antimicrobial peptide

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CAMP, cathelicidin antimicrobial peptide
Synonyms

CAP-18, CAP18, CRAMP, FALL-39, FALL39, HSD26, LL37
Links

HGNC:1472

NCBI Gene ID: 820

UniProt: P49913
Chr Location

3p21.31; chr3:48223347-48225491 (+) GRCh38

MGI Vertebrate Homology

Camp stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: CAMP
Gene Tree

Camp

less

Phenotype Summary

7 phenotypes from 2 alleles in 3 genetic backgrounds
76 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

32
Endonuclease-mediated

7
Gene trapped

17
Targeted

8
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

16 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Mice homozygous for a knock-out allele are more susceptible to necrotic skin infection caused by Group A Streptococcus and urinary tract infection caused by uropathogenic E. coli and F. solani-induced keratitis.

less

All GO Annotations

88
GO References

14

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

619
Tissues

19
cDNA Data

16
Literature Summary

3

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

less

All Sequences

33
RefSeq

2
UniProt

2
CCDS

CCDS52934.1

Ensembl

ENSMUSG00000038357 (Evidence)
NCBI Gene

12796

			Length	Strain/Species	Flank
genomic	12796	NCBI Gene Model \| MGI Sequence Detail	2080	C57BL/6J	± kb
transcript	NM_009921	RefSeq \| MGI Sequence Detail	599	ZRU/MplStud
polypeptide	P51437	UniProt \| EBI \| MGI Sequence Detail	172	Not Applicable

less

UniProt

2 Sequences
Protein Ontology

PR:000025851 cathelicidin antimicrobial peptide

(term hierarchy)
InterPro Domains

IPR022746 Cathelicidin, antimicrobial peptide, C-terminal

IPR018216 Cathelicidin, conserved site

IPR001894 Cathelicidin-like

IPR046350 Cystatin superfamily

less

All nucleic 20

cDNA 17

Primer pair 2

Other 1

Antibodies 1

Microarray probesets 3

less

MGD-MRK-37487, MGI:892985

Summaries

All 124

Developmental Gene Expression 3

Gene Ontology 14

Phenotypes 76
Earliest

J:34599 Popsueva AE, et al., A novel murine cathelin-like protein expressed in bone marrow. FEBS Lett. 1996 Aug 5;391(1-2):5-8
Latest

J:387154 Mishra AA, et al., Microbiota-derived short-chain fatty acids mediate Candida albicans gastrointestinal colonization resistance. Cell Host Microbe. 2026 Jun 4;

TSS for Camp:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr91589	Chr9:109678508-109678522 (-)	9 bp
Tssr91588	Chr9:109677768-109677778 (-)	751 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/01/2026 MGI 6.24