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Camp
Gene Detail
 Symbol
Name
ID
Camp
cathelicidin antimicrobial peptide
MGI:108443
Synonyms CAP18, Cnlp, Cramp, FALL39, MCLP
Feature Type protein coding gene
Genetic Map
Chromosome 9
59.80 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:109847375-109849456 bp, - strand
From VEGA annotation of GRCm38

  2082 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:110678  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 9 cattle; 1 dog

Gene Tree: Camp

Human
homologs
Human Homolog CAMP, cathelicidin antimicrobial peptide
NCBI Gene ID 820
neXtProt AC  NX_P49913
Human Synonyms  CAP18, CAP-18, CRAMP, FALL39, FALL-39, LL37
Human Chr (Location)  3p21.3; chr3:48223347-48225491 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Gene trapped(17) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele are more susceptible to necrotic skin infection caused by Group A Streptococcus and urinary tract infection caused by uropathogenic E. coli and F. solani-induced keratitis.
 
Interactions
Camp interacts with 4 markers (Mir208b, Mir875, Mir1224, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process antibacterial humoral response, defense response, ...
Component cell projection, cytoplasm, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (22)    Tissues (19)    Images (4)
Theiler Stages: 20, 21, 22, 23, 24, 26, 28
Assay TypeResults
Immunohistochemistry 3
Northern blot 7
RT-PCR 12
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) cDNA(16) Primer pair(2) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000020575 (Evidence)
Ensembl Gene ModelENSMUSG00000038357 (Evidence)
Entrez Gene12796 (Evidence)
UniGene3834
DFCITC1580444
DoTSDT.530614
NIA Mouse Gene IndexU031357
Consensus CDS ProjectCCDS52934.1
International Mouse Knockout Project StatusCamp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020575 VEGA Gene Model | MGI Sequence Detail 2082 C57BL/6J ±  kb
transcript OTTMUST00000048760 VEGA | MGI Sequence Detail 601 Not Applicable 
polypeptide OTTMUSP00000022449 VEGA | MGI Sequence Detail 172 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(2)
Polymorphisms RFLP(1) : SNPs within 2kb(41 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001894 Cathelicidin
InterPro IPR022746 Cathelicidin, antimicrobial peptide, C-terminal
InterPro IPR018216 Cathelicidin, conserved site
Protein Ontology PR:000025851 cathelicidin antimicrobial peptide
References (Earliest) J:34599 Popsueva AE, et al., A novel murine cathelin-like protein expressed in bone marrow. FEBS Lett. 1996 Aug 5;391(1-2):5-8
(Latest) J:199719 Kolar SS, et al., Protective role of murine beta-defensins 3 and 4 and cathelin-related antimicrobial peptide in Fusarium solani keratitis. Infect Immun. 2013 Aug;81(8):2669-77
All references(69)
Other
accession IDs
MGD-MRK-37487, MGI:892985

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory