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Camp Gene Detail
Summary
  • Symbol
    Camp
  • Name
    cathelicidin antimicrobial peptide
  • Synonyms
    CAP18, Cnlp, Cramp, FALL39, MCLP
  • Feature Type
    protein coding gene
  • IDs
    MGI:108443
    NCBI Gene: 12796
  • Gene Overview
    MyGene.info: CAMP
Location & Maps
more
  • Sequence Map
    Chr9:109847379-109849617 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2239 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 59.80 cM
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CAMP, cathelicidin antimicrobial peptide
  • Vertebrate Orthologs
    15
  • Human Ortholog
    CAMP, cathelicidin antimicrobial peptide
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CAP18, CAP-18, CRAMP, FALL39, FALL-39, HSD26, LL37
  • Links
    NCBI Gene ID: 820
    neXtProt AC: NX_P49913

  • Chr Location
    3p21.3; chr3:48223347-48225491 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 2 alleles in 3 genetic backgrounds
    40 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    21
  • Gene trapped
    17
  • Targeted
    4
  • Incidental Mutations
Mice homozygous for a knock-out allele are more susceptible to necrotic skin infection caused by Group A Streptococcus and urinary tract infection caused by uropathogenic E. coli and F. solani-induced keratitis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020575 VEGA Gene Model | MGI Sequence Detail 2239 C57BL/6J ±  kb
transcript OTTMUST00000048760 VEGA | MGI Sequence Detail 758 Not Applicable  
polypeptide OTTMUSP00000022449 VEGA | MGI Sequence Detail 172 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    44 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR001894 Cathelicidin
    IPR022746 Cathelicidin, antimicrobial peptide, C-terminal
    IPR018216 Cathelicidin, conserved site
Molecular
Reagents
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  • All nucleic 19
    cDNA 16
    Primer pair 2
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-37487, MGI:892985
References
more
  • Summaries
    All 69
    Developmental Gene Expression 1
    Gene Ontology 10
    Phenotypes 40
  • Earliest
    J:34599 Popsueva AE, et al., A novel murine cathelin-like protein expressed in bone marrow. FEBS Lett. 1996 Aug 5;391(1-2):5-8
  • Latest
    J:230974 Talreja D, et al., In Vivo Role of TLR2 and MyD88 Signaling in Eliciting Innate Immune Responses in Staphylococcal Endophthalmitis. Invest Ophthalmol Vis Sci. 2015 Mar;56(3):1719-32

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory