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Slbp Gene Detail
Summary
  • Symbol
    Slbp
  • Name
    stem-loop binding protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:108402
    NCBI Gene: 20492
  • Gene Overview
    MyGene.info: SLBP
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:33640055-33652574 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 17.83 cM, cytoband B1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    74 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108402
protein coding gene Chr5:33634952-33652574 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029449
protein coding gene Chr5:31818601-31840668 (-)
A/J MGP_AJ_G0029416
protein coding gene Chr5:30786980-30805517 (-)
AKR/J MGP_AKRJ_G0029365
protein coding gene Chr5:31974163-31993152 (-)
BALB/cJ MGP_BALBcJ_G0029426
protein coding gene Chr5:31316594-31335451 (-)
C3H/HeJ MGP_C3HHeJ_G0029148
protein coding gene Chr5:32013416-32033582 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029880
protein coding gene Chr5:33702511-33727463 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027117
protein coding gene Chr5:28588356-28605768 (-)
CAST/EiJ MGP_CASTEiJ_G0028557
protein coding gene Chr5:31092079-31112196 (-)
CBA/J MGP_CBAJ_G0029116
protein coding gene Chr5:34419482-34441905 (-)
DBA/2J MGP_DBA2J_G0029264
protein coding gene Chr5:30965478-30984103 (-)
FVB/NJ MGP_FVBNJ_G0029223
protein coding gene Chr5:30391392-30409462 (-)
LP/J MGP_LPJ_G0029349
protein coding gene Chr5:32243064-32264965 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029253
protein coding gene Chr5:35273017-35294542 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029913
protein coding gene Chr5:31487347-31506683 (-)
PWK/PhJ MGP_PWKPhJ_G0028282
protein coding gene Chr5:30099500-30117591 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028113
protein coding gene Chr5:30942820-30959870 (-)
WSB/EiJ MGP_WSBEiJ_G0028638
protein coding gene Chr5:31550170-31569106 (-)



Homology
more
  • Human Ortholog
    SLBP, stem-loop binding protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLBP, stem-loop binding protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HBP
  • Links
    NCBI Gene ID: 7884
    neXtProt AC: NX_Q14493
    UniProt: Q14493

  • Chr Location
    4p16.3; chr4:1692731-1712741 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 31389
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SLBP
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
  • All Mutations and Alleles
    14
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    2
  • Gene trapped
    4
  • Radiation induced
    3
  • Spontaneous
    1
  • Targeted
    3
  • Genomic Mutations
    7 involving Slbp
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20492 NCBI Gene Model | MGI Sequence Detail 12520 C57BL/6J ±  kb
transcript NM_009193 RefSeq | MGI Sequence Detail 1921 C57BL/6  
polypeptide P97440 UniProt | EBI | MGI Sequence Detail 275 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    8 Sequences
  • InterPro Domains
    IPR029344 Histone RNA hairpin-binding protein, RNA-binding domain
    IPR026502 Histone RNA stem-loop-binding protein SLBP1/SLBP2
    IPR038294 SLBP, RNA-binding domain superfamily
Molecular
Reagents
less
  • All nucleic 137
    cDNA 136
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-37444
References
more
  • Summaries
    All 56
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 7
    Phenotypes 26
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:225909 Jang CW, et al., Histone H3.3 maintains genome integrity during mammalian development. Genes Dev. 2015 Jul 1;29(13):1377-92

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory