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Slbp Gene Detail
Summary
  • Symbol
    Slbp
  • Name
    stem-loop binding protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:108402
    NCBI Gene: 20492
  • Gene Overview
    MyGene.info: SLBP
Location & Maps
more
  • Sequence Map
    Chr5:33634952-33652574 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      17623 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 17.83 cM, cytoband B1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SLBP, stem-loop binding protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLBP, stem-loop binding protein
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HBP
  • Links
    NCBI Gene ID: 7884
    neXtProt AC: NX_Q14493

  • Chr Location
    4p16.3; chr4:1692800-1712694 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 31389
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: SLBP
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
  • All Mutations and Alleles
    15
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    2
  • Gene trapped
    4
  • Radiation induced
    4
  • Spontaneous
    1
  • Targeted
    3
  • Genomic Mutations
    8 involving Slbp
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025101 VEGA Gene Model | MGI Sequence Detail 17623 C57BL/6J ±  kb
transcript OTTMUST00000061741 VEGA | MGI Sequence Detail 1906 Not Applicable  
polypeptide OTTMUSP00000030353 VEGA | MGI Sequence Detail 275 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    75 from dbSNP Build 142
Protein
Information
less
  • UniProt
    9 Sequences
  • Protein Ontology
    PR:000014916 histone RNA hairpin-binding protein
  • InterPro Domains
    IPR029344 Histone RNA hairpin-binding protein, RNA-binding domain
    IPR026502 Histone RNA stem-loop-binding protein SLBP1/SLBP2
Molecular
Reagents
less
  • All nucleic 135
    cDNA 135

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-37444
References
more
  • Summaries
    All 34
    Developmental Gene Expression 5
    Diseases 1
    Gene Ontology 5
    Phenotypes 26
  • Earliest
    J:37146 Wang ZF, et al., The protein that binds the 3' end of histone mRNA: a novel RNA-binding protein required for histone pre-mRNA processing. Genes Dev. 1996 Dec 1;10(23):3028-40
  • Latest
    J:225909 Jang CW, et al., Histone H3.3 maintains genome integrity during mammalian development. Genes Dev. 2015 Jul 1;29(13):1377-92

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory