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Mlx
Gene Detail
 Symbol
Name
ID
Mlx
MAX-like protein X
MGI:108398
Synonyms bHLHd13, BigMax alpha, Tcfl4
Feature Type protein coding gene
Genetic Map
Chromosome 11
64.18 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:101087277-101092207 bp, + strand
From VEGA annotation of GRCm38

  4931 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7969  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Mlx

Human
homologs
Human Homolog MLX, MLX, MAX dimerization protein
NCBI Gene ID 6945
neXtProt AC  NX_Q9UH92
Human Synonyms  bHLHd13, MAD7, MXD7, TCFL4
Human Chr (Location)  17q21.1; chr17:42567060-42573203 (+)  GRCh38
Alleles
and
phenotypes
All alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process negative regulation of transcription, DNA-templated, negative regulation of transcription from RNA polymerase II promoter, ...
Component cytoplasm, nucleus
Function DNA binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (167)    Tissues (157)    Images (16)
Theiler Stages: 2, 3, 4, 5, 16, 18, 21, 22, 23, 24, 26, 28
Assay TypeResults
RNA in situ 152
RT-PCR 15
cDNA source data(17)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(19) cDNA(18) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000002688 (Evidence)
Ensembl Gene ModelENSMUSG00000017801 (Evidence)
Entrez Gene21428 (Evidence)
NIA Mouse Gene IndexU013356
Consensus CDS ProjectCCDS25447.1, CCDS48935.1, CCDS48936.1
International Mouse Knockout Project StatusMlx
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002688 VEGA Gene Model | MGI Sequence Detail 4931 C57BL/6J ±  kb
transcript OTTMUST00000005288 VEGA | MGI Sequence Detail 1965 Not Applicable 
polypeptide OTTMUSP00000002511 VEGA | MGI Sequence Detail 298 Not Applicable 

For the selected sequences
All sequences(60) RefSeq(8) UniProt(7)
Polymorphisms SNPs within 2kb(32 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Protein Ontology PR:000010458 max-like protein X
References (Earliest) J:37128 Bjerknes M, et al., TCFL4: a gene at 17q21.1 encoding a putative basic helix-loop-helix leucine-zipper transcription factor. Gene. 1996 Nov 28;181(1-2):7-11
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)
Other
accession IDs
MGD-MRK-37440, MGI:1861754

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory